1. Course Description:
This course will focus on the recent progresses of both the clinical and basic researches of
neurodegenerative diseases. Several commonly known disorders such as Alzheimer's disease, Parkinson's
disease, and polyglutamine diseases will be selected as examples of how to study these devastated
disorders.

2. Textbooks and References:
The instructor will prepare handouts that covered research articles and outlines for the students, and
there is no assigned textbook. Nevertheless, the instructor will encourage students to refer the following
books for additional information.
(1). Molecular Mechanisms of Neurodegenerative Diseases, by Marie-Francoise Chesselet.
Publisher: Humana Press (January 15, 2001).
ISBN: 0896038041.
(2). Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics, by M. Flint Beal, Anthony
E. Lang, Albert C. Ludolph.
Publisher: Cambridge University Press (June 2, 2005).
ISBN: 052181166X.

3. Teaching Methods and Syllabus:
This course will be given in English and the students are assumed to be able to comprehend the lectures.
The instructor will divide the course into lecture and discussion, which will include the presentation of
research articles by students. The instructor will discuss the following topics in depth:
(1). Overview of neurodegenerative diseases.
(2). Alzheimer’s disease.
(3). Parkinson’s disease.
(4). Huntington’s disease and other polyglutamine disorders.
(5). Motor neuron diseases.

4. Evaluation:
Examines will be conducted in both written format and oral presentation.