一、課程說明(Course Description)
本課程主要介紹醫用病毒學原理如病毒組成與結構,分類,RNA或DNA病毒的分子複製機制.同時著重於探討引起人類疾病之重要病毒,病毒與細胞相互關係,病毒毒力與致病機轉,及抗病毒藥物與疫苗發展
The objective of this course is to learn the general principles and procedures
of virology, with emphasis on the viruses which cause human diseases. Topics in
general virology, such as virus replication, propagation, detection, assay,
classification, virus-host interactioins, immunology, pathogenesis and techniques will be considered first, followed by a discussion of the individual viruses and the diseases they cause in human.



二、指定用書(Text Books)
Principles of Virology: Molecular Biology, Pathogenesis, and Control, by
Flint, Wnquist, Krug, Racaniello, and Skalaka
ASM Press, 2004 (2nd edition)



三、參考書籍(References)




四、教學方式(Teaching Method)

class lectures



五、教學進度(Syllabus)

Chap 1: Foundations of Virology (Wu)
Chap 2: Virus cultivation, detection, and genetics (Wu)
Chap 3: Genome (Wu)
Chap 4: Structure (Yin)
Chap 5: Virus attachment and entry into cells (Yin)
Chap 6: Genome replication and mRNA production by RNA viruses (Yin)
Chap 7: Reverse transcription and intergration: hallmarks of the retroid viruses (Yin)
Chap 8: Transcription strategies: DNA templates (Yin)
Chap 9: Genome replication strategies: DNA viruses (Yin)
Chap 10: Processing of viral pre-mRNA (Wu)


六、成績考核(Evaluation)

Exam I Prof Yin's lectures (66.7%)
Exam II Prof Wu's lectures (33.3%)


七、可連結之網頁位址