一、課程說明(Course Description)

The course is designed to introduce students to the fundamentals of BioMEMS and lab-on-a-chip (LOC). Basic concepts of micro/nano fabrication of BioMEMS, microfluidic devices, on-chip biochemical detection techniques, and integration of lab-on-a-chip will be introduced and discussed. Various BioMEMS devices, lab-on-a-chip, uTAS and their applications will be covered. Students will gain a broad perspective in the area of micro/nano systems for biomedical and chemical applications.


二、指定用書(Text Books)

Class notes and handouts

三、參考書籍(References)

G. T. A. Kovacs, Micromachined Transducers Source Book, McGraw-Hill, 1998
S. S. Saliterman, Fundamentals of BioMEMS and Medical Microdevices, SPIE Press, 2006
M. J. Heller, and A. Guttman, Integrated Microfabricated Biodevices - advanced technologies for genomics, drug discovery, bioanalysis, and clinical diagnostics, Marcel Dekker, 2002

四、教學方式(Teaching Method)

Lecture

五、教學進度(Syllabus)

1. Introduction to BioMEMS and Lab-on-a-Chip (LOC)
2. Micro/Nano Fabrication Technologies of BioMEMS and Lab-on-a-Chip
3. Biocompatibility of Polymers
4. Micro/Nano Fluidics and Components
5. On-Chip Biochemical Sensing Principles
6. On-Chip Sample Preparation
7. Integration and Packaging of BioMEMS and Lab-on-a-Chip
8. Metabolic Point-of-Care Testing (POCT) Diagnostic Kit
9. Proteomics and Protein Lab-on-a-Chip

六、成績考核(Evaluation)

Homework 24%, Quiz 16%, Midterm exam 30%, Final project 30%