訊息傳遞專題研究一
<br> Current Topics in Signal Transduction              Jui-Chou Hsu
<br>This is a course to discuss the latest advance in the field of cell and developmental biology using mice, Xenopus, Drosophila, and C elegans as model organisms. The following are the example of literatures discussed and will be updated at the beginning of the classes.
<br>(1)	aPKC controls microtubule organization to balance adherens junction symmetry and planar polarity during development. Developmental Cell 12, 727-738, 2007
<br>(2) A molecular mechanism directly linking E-cadherin adhesion to initiation of epithelial cell surface polarity. J. Cell Biology 178, 323-335, 2007.
<br>(3) Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic. Nature Cell Biology 9, 1066-1073, 2007.
<br>(4) Gap junction adhesion is necessary for radial migration in the neocortex. Nature 448, 901-907, 2007.
<br>(5) Two distinct modes of guidance signalling during collective migration of border cells. Nature 448, 362-365, 2007.
<br>(6) Sequential pulses of apical epithelial secretion and endocytosis drive airway maturation in Drosophila. Developmental Cell 13, 214-225, 2007.
<br>(7) Genetic control of single lumen formation in the zebrafish gut. Nature Cell Biology 9, 954-960, 2007.
<br>(8) Spatial regulation of an E3 unbquitin ligase directs selective synapse elimination. Science 317, 947-951, 2007.
<br>(9) Rewiring cellular morphology pathways with synthetic guanine nucleotide exchange factors. Nature 447, 596-600, 2007.
<br>(10) A turnable genetic switch based on RNAi and repressor proteins for regulating gene epression in mammalian cells. Cell 130, 363-372, 2007.
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