一、課程說明(Course Description)
本課程為分子生物學二(LS3401)之延續課程,本課程共分三部份,第一部份涵蓋基因轉錄後之修飾機制。第二部份涵蓋基因轉譯為蛋白質之機制。第三部份涵蓋DNA replication, recombination and transposition.


二、指定用書(Text Books)

Molecular Biology by R. F. Weaver 2005. Third edition. Publisher:
WCB/McGraw Hill


三、參考書籍(References)

1. Molecular Cell Biology, by Lodish et al. 2003. Publisher: W. H. Freeman and
Company.
2. Molecular biology of the gene by Watson et al. 2004, Fifth edition.
Publisher: Benjamin cummings



四、教學方式(Teaching Method)

以指定教科書為主,討論各topic之研究方法、結論及其在分子生物學上之重要性。預期學生除結論外,也能瞭解現今之研究方向及實驗之方法。



五、教學進度(Syllabus)
Molecular and Cellular Biology III, LS3402, Spring, 2007
Instructors: Dr. Hai-Mei Huang, Tel: 42479
Dr. Dah-Tsyr Chang, Tel: 42767
Dr. Wei-Yuan Chow, Tel: 42687


Date Topics
2/27T 13 chromatin structure and its effect on transcription Dr. Chou
3/2 F 13 chromatin structure and its effect on transcription Dr. Chou
3/6 T 13 chromatin structure and its effect on transcription Dr. Chou
3/13T 14 posttranscriptional events I: splicing Dr. Chou
3/16F 14 posttranscriptional events I: splacing Dr. Chou
3/20T 15 posttranscriptional events II: capping and polyadenylation Dr. Chou
3/23F 15 posttranscriptional events II: capping and polyadenylation Dr. Chou
3/27T 16 posttranscriptional events III: other events Dr. Chou
3/30F 16 posttranscriptional events III: other events Dr. Chou
4/3 T 17 the mechanism of translation I: initiation Dr. Chang
4/10T 17 the mechanism of translation I: initiation Dr. Chang
4/13F Examination I (lecture 2/27 to 3/30) Dr. Chou 4/17T 17 the mechanism of translation I: initiation Dr. Chang
4/20F 18 the mechanism of translation II:elongation and termination Dr. Chang
4/24T 18 the mechanism of translation II:elongation and termination Dr. Chang
4/27F 18 the mechanism of translation II:elongation and termination Dr. Chang
5/1 T 19 ribosome and transfer RNA Dr. Chang
5/4 F 19 ribosome and transfer RNA Dr. Chang
5/8 T 19 ribosome and transfer RNA Dr. Chang
5/11F Examination II (lecture 4/3 to 5/8) Dr. Chang
5/15T 20 DNA replication I: mechanism and enzymology Dr. Chow
5/18F 20 DNA replication I: mechanism and enzymology Dr. Chow
5/22T 20 DNA replication I: mechanism and enzymology Dr. Chow
5/25F 21 DNA replication II: detailed mechanism Dr. Chow
5/29T 21 DNA replication II: detailed mechanism Dr. Chow
6/1 F 22 homologous recombination Dr. Chow
6/5 T 22 homologous recombination Dr. Chow
6/8 F 23 transposition Dr. Chow
6/12T 23 transposition Dr. Chow
6/15F 24 genomics Dr. Chow
6/22F Examination III (lecture 5/15 to 6/15) Dr. Chow



六、成績考核(Evaluation)

The grade is the average of three examinations.

助教: to be announced



七、可連結之網頁位址

參考書籍置於生科系圖書館,學生可向圖書館小姐借閱。
http://www.life.nthu.edu.tw/~labcwy/teaching.html