一、課程說明(Course Description)
結構生物學門的目光近年來聚焦在膜蛋白上,許多膜蛋白的研究為結構生物學門帶來了新衝擊。本課程將討論細胞膜上
重要蛋白質的結構,及其如何調控重大的生理功能,引起相關疾病。

二、指定用書(Text Books)
Mary Luckey “Membrane Structural Biology”

三、參考書籍(References)
Reinhard Grisshammer and Susan K Buchanan "Structural Biology of Membrane Proteins"

四、教學方式(Teaching Method)
上課講解加上個案報告

五、教學進度(Syllabus)
1. Membrane architecture.
2. Basic principles for membrane protein structure.
3. Method to study membrane protein structure.
4. Proteins in or at the membrane.
5. Protein folding and stability in the membrane.
6. Protein assembly: bundles and barrels.
7. Functions and families.
8. Membrane enzymes and transducers.
9. Transporters and channels.
10. Nanomachines on Membrane.
11. Membrane trafficking and related signal transduction.

六、成績考核(Evaluation)
考試及報告

七、可連結之網頁位址