一、課程說明(Course Description)
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<br>This two-hour lecture offers in-depth knowledge and current progress in the field of cytoskeletal-related 
<br>research in the context of signal transduction and human diseases. The first part of the course will focus 
<br>on the fundamental aspects of the cytoskeleton, including structure, function and dynamics. The second 
<br>part will introduce the emerging concept that the cytoskeleton serves as a signalling platform. 
<br>In the third part, course will be centered on mutations in the cytoskeleat proteins and how these 
<br>mutations cause a wide range of human diseases.
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<br>二、指定用書(Text Books)
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<br>No
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<br>三、參考書籍(References)
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<br>No
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<br>四、教學方式(Teaching Method)
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<br>This course is intended to offer students with knowledge in the field of cytoskeletal research beyond 
<br>texbook. The teaching contents will come from most recent review articles, including Nature Rev. Mol. Cell 
<br>Biol.,  J Clinic. Investigation, Trends in Cell Biology and Curr Opin  Cell Biol. This course will be offered in 
<br>English. We also invite lecturers from Department of Biomedical Engineering and environmental Science 
<br>and from National Chiao-Tung University to share their expertise in this field. Teaching is in English.
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<br>五、教學進度(Syllabus)
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<br>1. An overview of the cytoskeletal system
<br>2. Microtubule and its associated proteins 
<br>3. The many faces of actin
<br>4. The cytoskeletal proteins in the muscle
<br>5. Intermediate filament cytoskeleton 
<br>6. The cytoskeletal crosstalk and signal transduction 
<br>7. Cell migration and signal transduction 
<br>8. Cytoskeletal signaling in stress 
<br>9. Cytoskeletal signalling during cell growth
<br>10. Neuronal injury and signal transduction
<br>11. Cytoskeletal defects and human diseases 
<br>12. IF-relate diseases - desminopathies
<br>13. IF-related diseases – Astrogliopathies 
<br>14. Actinopathies and tauopathies
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<br>六、成績考核(Evaluation)
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<br>Attendance (20%)
<br>Mid-term report (40%)
<br>Final exam-oral presentation (40%)
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<br>七、可連結之網頁位址
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<br>eLearning