一、課程說明(Course Description)
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<br>本課程將從生科,化工,資訊,電機,統計的整合性角度探討 Systems Biology 的發展與研究. 課程自2003年開始後，已培訓許多來自各種不同教育背景的年輕研究人員，一起挑戰與生物、醫學相關的重要課題。此課程著重於結合理論推演及實驗量化驗證的訓練, 亦是[生物資訊學程]的一門重點課程。師資方面則集合來自生命科學、電機資訊、化工系統、與生物統計等系所的專任教授，以執行中的跨領域研究計畫為例，與學員一起學習探討生物體內的複雜機制及其如何調控因環境變化所誘發的反應與運作。
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<br>內容包括：
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<br>Introduction
<br>  1. Systems Biology in a nutshell
<br>L.S.:
<br>  1. Biological Networks and Biodatabases
<br>  2  Gene Regulatory Networks
<br>  3. Micro organisms
<br>  4. Host-pathogen interaction
<br>  5. Computational physiology
<br>C.H.E. and Stats:
<br>  1. Biostatistics
<br>  2. Network representation
<br>  3. Analysis modeling and identification
<br>  4. Model manipulation and control
<br>C.S. and E.E. :
<br>  1.  Robustness control
<br>  2.  Bio-model simulation
<br>  3.  Mapping and modeling tools
<br>  4.  Data integration
<br>  5.  Database construction and mining
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<br> 二、指定參考資料(Text Books)
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<br>Cell Designer (freeware) -- CellDesigner is a modeling tool of biochemical networks with graphical user interface. Supporting SBML (Systems Biology Markup Language) format and SBW (Systems Biology Workbench) compliant, you can conduct simulation seamlessly via Simulation menu as well as via SBW.
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<br>http://celldesigner.org/simulation.html
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<br> 三、參考書籍(References)
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<br>Systems Biology: Properties of Reconstructed Networks
<br>Bernhard O. Palsson
<br>ISBN: 0-521-85903-4
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<br> 四、教學方式(Teaching Method)
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<br>依序由 L.S.(5周) , C.H.E.(4週 ) , C.S.(5週) 教授課程, 
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<br> 五、教學進度(Syllabus)
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<br>Introduction,
<br>L.S. Course,
<br>Exam (Midterm Group Presentation)
<br>C.H.E. Course,
<br>C.S. Course,
<br>Student Presentation
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<br> 六、成績考核(Evaluation)
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<br>30% Midterm Group Presentation
<br>40% Final Group Presentation
<br>20% Final Report
<br>10% Attendance 
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<br> 七、可連結之網頁位址
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