細胞移動機制特論一
Mechanism of Cell Migration I Jui-Chou Hsu

This is a course to discuss the latest advance in the field of cell and developmental biology using mice, Xenopus, Drosophila, and C elegans as model to study cell migration. The following are the examples of papers discussed and will be updated later.

(1) Talk: A reiterative cellular mechanism for junction remodeling and cell displacement during morphogenesis
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(2) Pulsed forces timed by a ratchet-like mechanism drive directed tissue movement during dorsal closure. Cell 137, 1331-1342, 2009.
(3) Germline P granules are liquid droplets that localize by controlled sissolution.condensation. Science 324, 1729-1732, 2009.
(4) Switch in FGF signaling initiates glial differentiation in the Drosophila eye. Nature 460, 758-761, 2009.
(5) A genetically encoded photoactivatable Rac controls the motility of living cells Nature 461, 104-108, 2009 and Coordination of Rho GTPase activities during cell protrusion. Nature 461, 99-103, 2009.
(6) Integrin acts upstream of Netrin signaling to regulate formation of the anchor cell’s invasive membrane in C. elegans. Developmental Cell 17, 187-198, 2009.
(7) Linking asymmetric cell division to the terminal differentiation program of postmitotic neurons in C. elegans. Developmental Cell 16, 563-575, 2009.
(8) Caught at its own game: regulatory small RNA inactivated by an inducible transcript mimicking its target. Genes& Development 23, 2004-2015, 2009.
(9) Rab35 controls actin bundling by recruiting fascin as an effector protein. Science 325, 1250-1254, 2009.
(10) Identification of an Aurora-A/PinsLINKER/ Dlg Spindle Orientation Pathway using Induced Cell Polarity in S2 Cells Cell 138, 1150-1163, 2009.
(11) Fgf8 morphogen gradient forms by a source-sink mechanism with freely diffusing molecules. Nature 461, 533-536, 2009.