一、課程說明(Course Description)

免疫系統是一高度多樣化之防禦系統藉以清除致病性微生物及癌細胞。在這防禦系統中,各類特定功能的細胞與分子密切合作形成一動態的網絡,其複雜的程度不下於神經系統。近幾年,由於免疫學上多項突破性發現,使得這門科學漸趨成熟,而與神經科學並列為二十一世紀之顯學。無庸至疑地,免疫學是一不可缺少的生命科學課程。

本課程歡迎對免疫學有興趣但基礎較薄弱的大學部及研究生修習。亦至誠歡迎非生科系院同學選修。我們將以教科書為主,探討基本的免疫學現象及機制,簡言之,即是分子辨識(Molecular recognition) 與反應 (Response);並輔以介紹免疫學在生物醫學及產業的應用。

二、指定用書(Text Books)

Janeway's Immunobiology, 7th Edition, 2008; Garland Science; eds: Kenneth Murphy, Paul Travers, Mark Walport.

三、參考書籍(References)

Kuby Immunology, 6th Edition, 2007; W. H. Freeman and Company; eds: Thomas Kindt, Richard Goldsby, Barbara Osborne.

四、教學方式(Teaching Method)

Lectures/DVD/techniques and group presentation

五、暫定教學進度(Tentative Syllabus)

9/14 Introduction and grouping
9/21 Basic Concepts in Immunology and Innate Immunity
9/28 Teacher's Day; no class
10/5 Antigen Recognition by B-cell and T-cell Receptors and The Generation of Lymphocyte Antigen Receptors
10/12 Antigen Presentation to T Lymphocytes
10/19 The Development and Survival of Lymphocytes
10/26 Signaling Through Immune System Receptors
11/2 T Cell-Mediated Immunity
11/9 The Humoral Immune Response
11/16 Mid-term Exam
11/23 Immune Response to Infectious Diseases-Viral Infections
11/30 Immune Response to Infectious Diseases-Bacterial, Parasitic and Fungal Infections
12/7 Vaccines
12/14 Cancer and the Immune System
12/21 Transplantation Immunology, Tolerance and Autoimmunity
12/28 Group presentation 1-4
1/4 Group presentation 5-8
1/12 Term paper or home work

六、成績考核(Evaluation)
Tentative:
Exam 40%
Presentation 20%
Term paper or homework 20%
Presence and participation 20%

七、可連結之網頁位址

E-learning system