一、課程說明
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<br>課程內容包括重要酵素之結構與催化機制之關係以及酵素動
<br>&#63882;學。
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<br>二、指定用書
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<br>1. Fersht, A. (1999). Structure and Mechanism in Protein
<br>Science—A Guide to Enzyme catalysis and Protein Folding.
<br>Freeman.
<br>2. Silverman, R. B. (2000). The Organic Chemistry of Enzyme-
<br>Catalyzed Reactions. Academic Press.
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<br>三、&#63851;考書籍
<br>Current related literatures
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<br>四、教學方式
<br>Power Point Slides, Textbook and papers.
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<br>五、教學進&#64001;
<br>1. Introduction
<br>2. The organic chemistry of enzyme-catalyzed reactions (IIII)
<br>3. The three-dimensional structure of enzymes (I-III)
<br>4. Enzyme kinetics
<br>5. Measurement and magnitude of individual rate constant
<br>6. Practical methods for kinetics and equilibria
<br>7. Stereochemistry of enzymatic reactions (I-II)
<br>8. Special topics on enzyme structure (I-II)
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<br>
<br>&#63953;、成績考核
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<br>期中 (50%)、期末 (50%) 筆試。
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<br>七、講義位址
<br>http://