一、課程說明(Course Description)
<br>本課程為分子生物學二（LS3401）之延續課程，本課程共分三部份，第一部份涵蓋基因轉錄後之修飾機制。第二部份涵蓋基因轉譯為蛋白質之機制。第三部份涵蓋DNA replication, recombination and transposition.
<br>
<br>
<br>二、指定用書(Text Books)
<br>
<br>Molecular Biology by R. F. Weaver 2008. 4th edition. Publisher: 
<br>WCB/McGraw Hill
<br>
<br>
<br>三、參考書籍(References)
<br>
<br>1. Molecular Cell Biology, by Lodish et al. 2003. Publisher: W. H. Freeman and 
<br>   Company.
<br>2. Molecular biology of the gene by Watson et al. 2004, Fifth edition. 
<br>   Publisher: Benjamin cummings
<br>3. Recent papers related to the chapters in course.
<br>
<br>
<br>四、教學方式(Teaching Method)
<br>
<br>以指定教科書為主，討論各topic之研究方法、結論及其在分子生物學上之重要性。預期學生除結論外，也能瞭解現今之研究方向及實驗之方法。
<br>
<br>
<br>五、教學進度(Syllabus)- - page 1
<br>  Molecular and Cellular Biology III, LS3402, Spring, 2009
<br>  Instructors:	Dr. Haimei Huang, Tel: 4-2479, hmhuang@life.nthu.edu.tw;
<br>                  Dr. Ja-Ling Yang, Tel: 4-2756, jlyang@life.nthu.edu.tw;
<br>		Dr. Wei-Yuan Chow, Tel: 4-2687, wychow@life.nthu.edu.tw;
<br>
<br>
<br>Molecular Biology 2010 Spring (temporary)
<br>Textbook: 4th edition, Molecular Biology, by Robert F. Weaver
<br>
<br>Date		Chapter and Topics							
<br>2/23 T 13 chromatin structure and its effect on transcription    Dr. Huang
<br>2/26 F   13 chromatin structure and its effect on transcription  Dr. Huang
<br>3/02 T   13 chromatin structure and its effect on transcription  Dr. Huang
<br>3/05 F    School activity 		    
<br>3/09 T   14 posttranscriptional events I: splicing		  Dr. Huang
<br>3/12 F   14 posttranscriptional events I: splacing		  Dr. Huang
<br>3/16 T   15 posttranscriptional events II: 
<br>             capping and polyadenylation                       Dr. Huang
<br>3/19 F   15 posttranscriptional events II: Continued           Dr. Huang
<br>3/23 T   16 posttranscriptional events III: other events       Dr. Huang
<br>3/26 F   16 posttranscriptional events III: other events	 Dr. Huang (13)
<br>p.359~520 (Total 162 pages)~
<br>
<br>3/30 T   17 the mechanism of translation I: initiation	Dr. Yang 
<br>4/02 F    Spring break
<br>4/06 T   17 the mechanism of translation I: initiation	Dr. Yang 
<br>4/09 F   Examination I (lecture 2/23 to 3/26)		Dr. Huang 
<br>4/13 T   17 the mechanism of translation I: initiation	Dr. Yang
<br>4/16 F   18 the mechanism of translation II:
<br>            elongation and termination                        Dr. Yang
<br>4/20 T   18 the mechanism of translation II:Continued         Dr. Yang 
<br>4/23 F   18 the mechanism of translation II:Continued         Dr. Yang
<br>4/27T   19 ribosome and transfer RNA		         Dr. Yang
<br>4/30 F   19 ribosome and transfer RNA		         Dr. Yang
<br>5/04T   19 ribosome and transfer RNA		         Dr. Yang
<br>5/07 F   24 genomics      		            	         Dr. Yang
<br>5/11 T   24 genomics			  	         Dr. Yang (15)
<br>p.521~638, p.770-827 (Total 176 pages)~
<br>
<br>5/14F   20 DNA replication I: mechanism and enzymology         Dr. Chow
<br>5/18 T   20 DNA replication I: mechanism and enzymology	 Dr. Chow
<br>5/21 F   Examination II (lecture 3/30 to 5/11)                 Dr. Yang
<br>5/25T   20 DNA replication I: mechanism and enzymology	 Dr. Chow
<br>5/28 F   21 DNA replication II: detailed mechanism      	 Dr. Chow
<br>6/01 T   21 DNA replication II: detailed mechanism	          Dr. Chow
<br>6/04 F   22 homologous recombination            	          Dr. Chow
<br>6/08 T   22 homologous recombination			 Dr. Chow
<br>6/11 F   23 transposition           			 Dr. Chow
<br>6/15 T   23 transposition					 Dr. Chow
<br>6/18 F   No class (or flexible)                                Dr. Chow (13)
<br>6/22 T   Examination III (lecture 5/14 to 6/18)	          Dr. Chow 
<br>p.639~769 (Total 131 papges)
<br>
<br>6/23 W  教師送繳應屆畢業生本學期成績截止
<br>7/09 F    教師送繳非應屆畢業生本學期成績截止
<br>
<br>
<br>六、成績考核(Evaluation)
<br>
<br>The grade is the average of three examinations.
<br>
<br>助教： to be announced
<br>
<br>
<br>
<br> 七、可連結之網頁位址
<br>
<br>參考書籍置於生科系圖書館，學生可向圖書館小姐借閱。
<br>http://www.life.nthu.edu.tw/~labcwy/teaching.html
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>
<br>