LSMC 5353
<br>99年度第一學期
<br>細菌毒素研究
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<br>教師：王雯靜  
<br>時間：星期二9:00 am~12:00 pm
<br>地點：生科二館526室
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<br>     第   週	日  期	Topics
<br>	1	9/14	Introduction
<br>	2	9/21	Microbial virulence factors
<br>	3	9/28	Helicobacter pylori 
<br>	4	10/5	Virulence factors of H. pylori
<br>	5	10/12	Vacuolating toxin
<br>	6	10/19	AB-type toxins and pore-forming toxins
<br>	7	10/26	Bacillus anthracis  & Anthrax toxin 
<br>			Bordetella pertussis & Pertussis toxin
<br>			Corynebacterium diphtheriae & diphtheria toxin
<br>	8	11/2	Escherichia coli & heat-labile toxin, verotoxin
<br>			Shigella dysenteria & shiga toxin
<br>			Vibrio cholerae & cholera toxin
<br>	9	11/9	期中考			
<br>	10	11/16	Clostridium tetani & tetanus toxin
<br>			Clostridium botulinum & botulinum toxin
<br>	11	11/23	Campylobacter jejuni & cytolethal distending toxin
<br>	12	12/30	Pathogen-cell interaction
<br>	13	12/7	Phylogenetic perspectives in innate immunity
<br>	14	12/14	Secretion machines
<br>	15	12/21	Recent topics on bacterial virulence I
<br>	16	12/28	Recent topics on bacterial virulence II
<br>	17	1/4	Recent topics on bacterial virulence III
<br>	18	1/11	期末考
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<br>參考書本
<br>	1. Murray, P. R., Kobayashi, G. S., Pfaller, M. A. & Rosenthal, K. S. (1994). Medical Microbiology. Wolfe.
<br>	2. Alouf, J. E. and Freer, J. H. (1999). Bacterial protein toxins. Academic Press.
<br>	3. Evans, A. S. and Brachman, P. S. (1998). Bacterial Infectioins of Humans.  Epidemiology and Control. Plenum Medical
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