一、課程說明

課程內容包括重要酵素之結構與催化機制之關係以及酵素動
力學。

二、指定用書

1. Fersht, A. (1999). Structure and Mechanism in Protein
Science—A Guide to Enzyme catalysis and Protein Folding.
Freeman.
2. Silverman, R. B. (2000). The Organic Chemistry of Enzyme-
Catalyzed Reactions. Academic Press.

三、參考書籍
Current related literatures

四、教學方式
Power Point Slides, Textbook and papers.


五、教學進度
1. Introduction
2. The organic chemistry of enzyme-catalyzed reactions (IIII)
3. The three-dimensional structure of enzymes (I-III)
4. Enzyme kinetics
5. Measurement and magnitude of individual rate constant
6. Practical methods for kinetics and equilibria
7. Stereochemistry of enzymatic reactions (I-II)
8. Special topics on enzyme structure (I-II)


六、成績考核

期中 (50%)、期末 (50%) 筆試。


七、講義位址
http://