一、課程說明(Course Description)

The course is designed to provide the advanced students with knowledge and methods required for the design, fabrication and characterization of biosensors and bioelectronics for biochemical, biomedical, clinical and environmental applications. The fundamentals of molecular recognition, biomolecular immobilization, transduction mechanism will be covered in the discussion of various biosensors. In addition, the basic electronic biosignal conditioning circuits and processing methods will be introduced. The integration of bioelectronics with biosensors and bioarrays will be discussed to build lab-on-a-chip systems.


二、指定用書(Text Books)

Class notes and handouts

三、參考書籍(References)

1. W. Katz, Bioelectronics - From Theory to Applications, Wiley, 2005
2. Mauro Ferrari, BioMEMS and Biomedical Nanotechnology: Volume IV: Biomolecular Sensing, Processing and Analysis, Springer, 2006
3. George K. Knopf, Smart Biosensor Technology, CRC, 2006
4. Robert A. Freitas Jr., Nanomedicine, Volume IIA: Biocompatibility
5. J. J.Carr, Sensors and Circuits - Sensors, Transducers, and Supporting Circuits for Electronic Instrumentation, Measurement, and Control, PTR, 1993
6. Biosensors and Bioelectronics (Journal)



四、教學方式(Teaching Method)

Lecture

五、教學進度(Syllabus)

1.Introduction to Biosensors and Bioelectronics
2.Molecular Recognition and Bio-immobilization Principles
3.Physicochemical Transduction Mechanisms for Biotransductions
4.Nanotechnology for Medicine and Biology
5.Bio-Nano interfacing and Bio-Nano devices
6.Clinical Biosensors
7.Proteomics and Protein Biosensors
8.Cell-based Biosensors
9.Biomaterial-nanoparticle Hybrid Systems for Sensing and Electronic Devices



六、成績考核(Evaluation)

Presentations 20%, Project Reports 25%, Homeworks 30%,
Final exam 25%