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課程大綱:

一、課程說明 (Course Description)

This course is to provide the students an introduction to the fundamental concepts of controlled drug delivery systems, types of drug carriers that have been and/or are being developed and, particularly, detail descriptions in both the preparation approaches and mechanisms of their actions to achieve drug controlled delivery. For comprehensively understanding the rationales of drug delivery design with desired biodistribution profiles, pharmacokinetics and biopharmaceutics are partially introduced in this course.

二、指定用書 (Text Books)

No textbooks

三、參考書籍 (References)
1. R. Duncan, L. W. Seymour, Controlled Release Technology, Elsevier, 1989.
2. R. Baker, Controlled Release of Biologically Active Agents, Wiley, 1987.
3. L. Shargel, A. B. C. Yu, Applied Biopharmaceutics and Pharmacokinetics, 2nd Ed., ACC, 1985.


四、教學方式 (Teaching Method)

Lectures

五、教學進度 (Syllabus)

Contents
A. Controlled Release of Drugs
1. Concepts of drug controlled release
2. Drug targeting of water soluble polymeric delivery systems
3. Liposomes
4. Hydrogels
5. Microencapsulations
6. Other devices

B. Biopharmaceutics and Pharmacokinetics

六、成績考核 (Evaluation)

45% Midterm Exam
45% Final Exam
10% On-class discussion
100% Total


七、可連結之網頁位址