一、課程說明(Course Description)
<br>This course is designed for graduate students who have taken fundamental courses 
<br>in Microfluidics (such as PME 5170 Thermo-fluidics in Bio-MEMS). It will cover 
<br>advanced topics in microfluidics, including critical devices and integrated 
<br>systems. Their biomedical applications for DNA, RNA, proteins, and cells will be 
<br>extensively investigated. 
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<br>二、指定用書(Text Books)
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<br>三、參考書籍(References)
<br>1.	“ Microfluidic Technology and Applications (Microtechnologies and 
<br>Microsystems Series) “ by Michael Koch, et al., 2000.
<br>2.	"Microsensor - Principles and Applications", by J. W. Gardner, Wiley, 
<br>1996.
<br>3.	" Semiconductor Sensors", by S. M. Sze, John Wiley & Sons, Inc. , 1994
<br>4.	" Micromechanics and MEMS-classic and seminal papers to 1990", edited by 
<br>W. S. Trimmer, IEEE press, 1996.
<br>5.	"Fundamental of microfabrication", by Marc Madou, CRC press, New York, 
<br>1997.
<br>6.	"Micromachined Transducers- Sourcebook", by G. T. A. Kovacs, WCB/McGraw, 
<br>1998.
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<br>四、教學方式(Teaching Method)
<br>Lecture
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<br>五、教學進度(Syllabus)
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<br>1.	Introduction to microfluidics 
<br>2.	Review of microfabrication technologies for microfluidics- silicon-based 
<br>and non-silicon-based techniques
<br>3.	Case study on micro fabrication of simple fluidic devices---micro 
<br>channel, cavity, diaphragm etc.
<br>4.	Micro flow sensors
<br>(a)	Temperature sensors
<br>(b)	Pressure sensors
<br>(c)	Shear stress sensors
<br>(d)	Flow velocity sensors
<br>5.	Microfluidic devices
<br>(a)	Micro pumps
<br>(b)	Micro valves
<br>(c)	Micro mixers
<br>(d)	Micro nozzles
<br>(e)	Micro injectors
<br>(f)	Micro flow switches
<br>(g)	Micro bio-reactors
<br>(h)	Micro separators (micro capillary electrophoresis and micro-filters)
<br>6.	Microfluidic systems 
<br>(a)	flow cytometer
<br>(b)	protein chips
<br>(c)	DNA chips
<br>(d)	cell chips 
<br>7.	Special topics for microfluidic systems
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<br>六、成績考核(Evaluation)
<br>Homework                             30 %
<br>Midterm                               40 %   
<br>Final project & presentation                30 % 
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<br>七、可連結之網頁位址
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