1. Course description: Fruit fly is an invertebrate model system emerging as a powerful tool for dissecting 
<br>the function of human disease genes. Over the years, the fruit fly Drosophila researchers have developed 
<br>sophisticated genetic techniques that proven invaluable for the study of signaling pathways and 
<br>developmental biology. The knowledge obtained in fly is often connected to human biology because 
<br>pathways controlling among different species are virtually conserved. In this course, we will summarize 
<br>the recent advances in human disease researches that have been applying fly system as animal models. 
<br>We 
<br>will focus on cancer, type 2 diabetes, neurodegenerative disorders, and cardiac diseases. 
<br>
<br>2. Test books: None.
<br>
<br>3. References: None.
<br>
<br>4. Teaching method: Lecture will be given by the instructor to summarize the pathological mechanism of 
<br>diseases, and student will be assigned to present some research papers. All lectures and presentations are 
<br>in English.
<br>
<br>5. Syllabus: 
<br>Week 1~4: Modeling cancer and metastasis in Drosophila
<br>Week 5~8: Study type 2 diabetes in Drosophila
<br>Week 9~13: Neurological disorders and fly models
<br>Week 14~17: Drosophila as an emerging model for cardiac disease
<br>Week 18: Final
<br>
<br>6. Evaluation: 
<br>Oral presentation: 35%
<br>Participation: 15%
<br>Final exam: 50%
<br>
<br>
<br> 
<br>
<br>