一、課程說明(Course Description)
本課程為分子生物學二(LS3401)之延續課程,本課程共分三部份,第一部份涵蓋基因轉譯為蛋白質之機制。第二部份涵蓋基因轉錄後之修飾機制。第三部份涵蓋DNA replication, recombination and transposition.


二、指定用書(Text Books)

Molecular Biology by R. F. Weaver 2008. 5th edition. Publisher:
WCB/McGraw Hill


三、參考書籍(References)

Recent papers related to the chapters in course.


四、教學方式(Teaching Method)

以指定教科書為主,討論各topic之研究方法、結論及其在分子生物學上之重要性。預期學生除結論外,也能瞭解現今之研究方向及實驗之方法。


五、教學進度(Syllabus)- - page 1

Date Chapter and Topics Lecturer
2/19 T 17 (& 3, 19) ribosome, transfer RNA and messenger 楊嘉鈴
2/22 F 17 (& 3, 19) the mechanism of translation I: initiation 楊嘉鈴
2/26 T 17 (& 3, 19) the mechanism of translation I: initiation 楊嘉鈴
3/01 F School activity
3/05 T 17 the mechanism of translation I: control of initiation 楊嘉鈴
3/08 F 17 the mechanism of translation I: control of initiation 楊嘉鈴
3/12 T 18 (& 19) the genetic code 楊嘉鈴
3/15 F 18 (& 19) the mechanism of translation II: elongation 楊嘉鈴
3/19 T 18 (& 19) the mechanism of translation II: elongation 楊嘉鈴
3/22 F 18 translation II: termination/posttranslation 楊嘉鈴
3/26 T 18 translation II: termination/posttranslation 楊嘉鈴
3/29 F Examination I (lectures 2/19 to 3/26) 楊嘉鈴
4/02 T 13 chromatin structure and its effect on transcription 張鑑中
4/05 F Spring break
4/09 T 13 chromatin structure and its effect on transcription 張鑑中
4/12 F 13 chromatin structure and its effect on transcription 張鑑中
4/16 T 13 chromatin structure and its effect on transcription 張鑑中
4/19 F 14 posttranscriptional events I: splicing 張鑑中
4/23 T 14 posttranscriptional events I: splicing 張鑑中
4/26 F 15 posttranscriptional events II: capping and polyadenylation 張鑑中
4/30 T 15 posttranscriptional events II: capping and polyadenylation 張鑑中
5/03 F 16 posttranscriptional events III: other events 張鑑中
5/07 T 16 posttranscriptional events III: other events 張鑑中
5/10 F Examination II (lectures 4/02 to 5/07) 張鑑中
5/14 T 20 DNA replication I: mechanism and enzymology 周姽嫄
5/17 F 20 DNA replication I: mechanism and enzymology 周姽嫄
5/21 T 21 DNA replication II: detailed mechanism 周姽嫄
5/24 F 21 DNA replication II: detailed mechanism 周姽嫄
5/28 T 21 DNA replication II: detailed mechanism 周姽嫄
5/31 F 22 homologous recombination 周姽嫄
6/04 T 22 homologous recombination 周姽嫄
6/07 F 23 transposition 周姽嫄
6/11 T 23 transposition 周姽嫄
6/14 F 23 transposition 周姽嫄
6/21 F Examination III (lectures 5/11 to 6/12) 周姽嫄

六、成績考核(Evaluation)

The grade is the average of three examinations.

助教: to be announced


七、可連結之網頁位址
See the attached pdf files in iLMS