This is a course to discuss the latest advance in the field of cell and developmental biology using mice, Xenopus, Drosophila, and C elegans as model organisms.


(1) Cortical F-actin stabilization generates apical_lateral patterns of junctional contractility that integrate cells into epithelia. Nature Cell biology 16, 167, 2014.
(2) Mitochondrial ROS Regulates Cytoskeletal and Mitochondrial Remodeling to Tune Cell and Tissue Dynamics in a Model for Wound Healing. Dev. Cell 28, 239, 2014.
(3) Coupling of Rotational Cortical Flow, Asymmetric Midbody Positioning, and Spindle Rotation Mediates Dorsoventral Axis Formation in C. elegans. Dev. Cell. 28,253, 2014.
(4) PCP and Septins Compartmentalize Cortical Actomyosin to Direct Collective Cell Movement. Science 343, 649, 2014.
(5) An Equatorial Contractile Mechanism Drives Cell Elongation but not Cell Division. PLOS Biology 212, e1001781.
(6) A genome-wide screen identifies conserved protein hubs required for cadherin-mediated cell–cell adhesion. J. Cell Biol. 204, 265, 2014.
(7) Coordination of Rho Family GTPase Activities to Orchestrate Cytoskeleton Responses during Cell Wound Repair. Current Biology. 24, 144, 2014.
(8) Patterning and growth control by membrane-tethered Wingless. Nature, 505, 180, 2014.
(9) A Mechanism for Reorientation of Cortical Microtubule Arrays Driven
by Microtubule Severing. Science. 342, 1202, 2013.
(10) Tension-oriented cell divisions limit anisotropic tissue tension in epithelial spreading during zebra_sh epiboly. Nature Cell Biol. 15, 1405, 2013
(11) Principles of E-Cadherin Supramolecular Organization In Vivo. Current Biology. 23, 2197, 2013.