生物發育機制專題研究二        Jui-Chou Hsu
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<br>This is a course to discuss the latest advance in the field of cell and developmental biology using mice, Xenopus, Drosophila, and C elegans as model organisms.
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<br>(1)	Pulsed contractions of an actin–myosin network drive apical constriction.
<br>  Nature 457, 49, 2009.
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<br>(2)	Differential positioning of adherens junctions is associated with initiation of epithelial folding. Nature  484, 390, 2012
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<br>(3)	Oscillation and Polarity of E-Cadherin Asymmetries Control Actomyosin Flow Patterns during Morphogenesis. Dev cell, 26, 162, 2013.
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<br>(4)	Cortical F-actin stabilization generates apical–lateral patterns of junctional contractility that integrate cells into epithelia. Nature cell boil, 16, 167, 2014.
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<br>(5)	Dynamic myosin phosphorylation regulates contractile pulses and tissue integrity during epithelial morphogenesis.  J cell Biol. 206, 435, 2014. 
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<br>(6)	Actin dynamics modulate mechanosensitive immobilization of E-cadherin at adherens junctions. Nature cell boil. 16, 584, 2014.
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<br>(7)	Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation. Nature 508, 392, 2014.
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<br>(8)	Radial intercalation is regulated by the Par complex and the microtubule-stabilizing protein CLAMP/Spef1.  J cell Biol. 206, 367, 2014.
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<br>(9)	CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover. Nature cell boil. 16, 558, 2014.
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<br>(10)	Plasma membrane phosphoinositide balance regulates cell shape during Drosophila embryo morphogenesis. J cell Biol. 205, 395, 2014.
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