一、課程說明		
<br>Familiarize students to genomic methods. 
<br>Encourage students to think on genomic scale. 
<br>Excite students about hottest areas of biology. 
<br>Demystify modern methods and concepts. 
<br>Introduce necessary jargon but keep it to a minimum. 
<br>Foster experimental design in genomics. 
<br>Discover basic biology in the context of applied research. 
<br>Use case study method to extract concepts. 
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<br>二、指定用書	
<br>“Discovering Genomics, Proteomics and Bioinformatics (2nd Edition)” 
<br>A. Malcolm Campbell and Laurie Heyer. ISBN No. 0805382194 
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<br>三、參考書籍	
<br>Structural and Evolutionary Genomics 
<br>The Regulatory Genome : Gene Regulatory Networks In Development And Evolution 
<br>Eric H. Davidson  ISBN No: 0120885638 
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<br>四、教學方式	
<br>投影片
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<br>五、教學進度	
<br>Part1: Genome Sequences
<br>1.	Human Genome Project: the moving force. 
<br>2.	HapMap Project: from genome sequence to variation. 
<br>3.	Current genomic technology. 
<br>Part2: Genome Expression
<br>4.	Basic Research with DNA Microarrays
<br>5.	Applied Research with DNA Microarrays 
<br>6.	Proteomics and biomarker discovery. 
<br>Part3: Whole Genome Perspective
<br>7.	Genomic Circuits in Single Genes
<br>8.	Integrated Genomic Circuits
<br>9.	Modeling Whole-Genome Circuits
<br>10.	Midterm exam.
<br>Part4: Cancer Genomics 
<br>11.	Cancer genomics (I) 
<br>12.	Cancer genomics (II)
<br>Part5: Pharmacogenomcis and Microbial genomics
<br>13.	Pharmacogenomcis
<br>14.	Microbial genomics
<br>Part6: Gene Regulatory Networks
<br>15.	The Structure/Function Basis of Regulatory Logic
<br>16.	Gene Regulatory Networks for Development
<br>17.	Gene Regulatory Networks and Evolution
<br>18.	Final exam. 
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<br>六、成績考核	
<br>出席率10 %，期中考30%，報告15 %，期末考45% 
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