疾病機制
Mechanisms of Disease

@ 修課年級: 醫科系,生科院學士班大學部 三 年級以上!

此特色課程為醫學科學系大學部高年級選修課程,預計選擇講授6~8個主題疾病。每個主題疾病邀請一位從事相關研究的院內專任教授主持,並由其邀請一位合作研究的臨床醫師,搭配共講。連續於兩週內,分別闡述該疾病之重要醫療課題及相關基礎研究,深入探討疾病機制。課程強調 ”fusing science with medicine”,以激發學生對相關醫學科學研究的興趣與熱忱。

一、課程說明
Understanding the molecular and cellular basis of diseases is vital for dissecting disease pathogenesis and for designing appropriate and effective treatments.
In a Series of specially commissioned lectures, we will introduce the current understanding of the molecular mechanisms that underlie a range of common human disorders, explores possible therapeutic targets and treatments, and discusses new technologies and resources to study disease mechanisms.

二、指定用書
無指定用書

三、參考資料
1. Mechanisms of Disease on the New England Journal of Medicine
http://www.nejm.org/medical-articles/mechanisms-of-disease
2. Mechanisms of Disease: an introduction to clinical science
Stephen Tomlinson, Anthony M. Heagerty, Anthony P. Weetman
Cambridge University Press, 2008

四、教學方式
Lectures and discussion

五、教學進度

主題1: Cancer and therapy: Lung cancer treatment and translational research
主題2: Cancer and biomarker
主題3: Cancer and mitochondria
主題4: Cancer and stem cells: The role of mesenchymal stem cells in tumor progression
Midterm exam
主題5: GI disease and pathogen: Helicobacter pylori infection and gastric diseases
主題6: Fungal pathogen
主題7: Anti-Inflammation/Anti-Angiogenesis and structural biology
Review
Final Examination

六、成績考核
Exam and reports

七、講義位址
iLMS數位學習平台 http://lms.nthu.edu.tw/