一、課程說明	Transcription Factor Forkhead Box (Fox) protein family members 
<br>regulate transcriptional network of genes control multiple cell physiology.  Among 
<br>them, FoxM1 and FoxO have been identified as important transcription factors in 
<br>development, cancer and other diseases.  This course aims to help students understand 
<br>the molecular mechanism and biological roles of FoxM1 and FoxO by covering the 
<br>following issues: 1) regulation of Forkhead box family transcription factors; 2) Fox 
<br>proteins transcriptional regulate cell cycle; 3) Fox target genes and regulatory 
<br>signal pathways; 4) Fox proteins in mouse embryonic development; 5) Fox proteins in 
<br>cancer biology; 6) Fox proteins oxidative stress and related diseases.
<br>二、指定用書	Selected papers
<br>三、參考書籍	Selected papers
<br>四、教學方式	Lecture/ Seminar /Discussion
<br>五、教學進度	
<br>3/02	Introduction to Fox transcription factors
<br>3/09	Discovery of Foxm1 and liver transcription factors
<br>3/16	Molecular analysis of FoxM1 protein
<br>3/23	Fox family in cell cycle regulation  
<br>3/30	Fox family, SCF and Protein degradation
<br>4/06	Fox family in lung and liver cancers
<br>4/3	Fox family in ovary and colorectal cancers 
<br>4/13	Fox family in embryo development
<br>4/20	Fox family in lung development and maturation
<br>4/27	Fox O and FoxM1 in oxidative stress response
<br>5/4	Fox O and FoxM1 in diabetes
<br>5/11	Aging Foxes
<br>5/18	Fox family in injury-repair process
<br>5/25	Fox and stem cells
<br>6/01	The crosstalk between FoxO and FoxM1
<br>6/08	Overview of the other Foxes
<br>6/15	Holiday
<br>6/22	Final exam/seminar
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<br>六、成績考核	Attendance10%
<br>Discussion/Seminar 30%
<br>Mid-term and Final report 60%
<br>七、講義位址
<br>    http://	
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