一、課程說明(Course Description)
<br>Focus on the emerging areas of lung epithelial biology and the critical issues on 
<br>normal lung development and diseases. Current subjects of lung research field 
<br>such as interaction of epithelia and stroma, immune interaction, as well as 
<br>regulatory signaling pathways will be introduced and discussed. The course aims 
<br>to help students understand the fundamental and molecular mechanism of health and 
<br>diseased lungs by covering following issues: (1) Lung epithelia development (2) 
<br>lung biology and maintenance of lung function (3) epithelia-mesenchyme 
<br>interaction (4) Acute and chronic pulmonary diseases (5) lung cancer initiation 
<br>and metastasis (6) normal lung stem cell and lung cancer stem cells. 
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<br>二、指定用書(Text Books)
<br>Selected papers
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<br>三、參考書籍(References)
<br>Selected papers
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<br>四、教學方式(Teaching Method)
<br>Lecture/ Seminar /Discussion
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<br>五、教學進度(Syllabus)
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<br>09/05 Overview of lung biology 
<br>09/12 Genetic control of lung development
<br>09/19 Branch morphogenesis and airway development
<br>09/26 Surfactant proteins and lipids in lung function
<br>10/03 Surfactants and Respiratory distress syndrome
<br>10/10 (National Holiday)
<br>10/17 Epithelial-mesenchymal interrelationships
<br>10/24 Lung homeostasis
<br>10/31 Acute lung injury, repair and regeneration
<br>11/07 Stem cells and epithelial cell plasticity
<br>11/14 COPD and pulmonary fibrosis
<br>11/21 Lung Inflammation and asthma 
<br>11/28 Overview of lung cancers 
<br>12/05 Transcriptional regulation in lung cancer initiation
<br>12/12 Transcriptional regulation in lung cancer metastasis
<br>12/19 Lung cancer mouse models 
<br>12/26 Lung cancer stem cell
<br>01/02 (Holiday)
<br>01/09 Lung cancer drug resistance/ Final report
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<br>六、成績考核(Evaluation)
<br>Attendance 20%
<br>Discussion/Seminar 60%
<br>Final report 20%
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