一、課程說明(Course Description)
<br>“Throughout the foreseeable future, research in medicine, molecular biology, 
<br>and biotechnology will be 
<br>dominated by scientific advancements resulting form the Human Genome 
<br>Project. Knowledge of genomes 
<br>will elucidate disease patterns and promises improved and personalized 
<br>treatments. Food and drug 
<br>development will be revolutionized by the focused manipulated of genes and 
<br>biochemical process.”
<br>– by Prof. Eberhard O. Voit.
<br>
<br>本課程兼重學理與實作，藉由習題與範例，使學員能熟悉網路上各種生物資訊之取得及應用，並針
<br>對各種常用生物資料
<br>庫作概略性的介紹，包括 NCBI, Protein Data Bank (PDB)、 KEGG、ExPasy 等生物資料
<br>庫。課程中將連線上網，實際
<br>操作、演練各種輔助軟體 (Browser, viewer, molecular displayer...)。
<br>部分內容需具有生科系本科生大二基礎，建議大三以上（含）修讀，學習效果較佳。
<br>
<br>二、參考書籍(References)
<br>1. Bioinformatics: a practical guide to the analysis of genes and proteins, 
<br>Third Edition 
<br>(http://as.wiley.com/WileyCDA/WileyTitle/productCd-0471478784.html)
<br>The reference is for Gene Module.
<br>
<br>三、教學方式(Teaching Method)
<br>在電腦教室上課，課堂講解示範與學生實地操做並行。
<br>
<br>四、成績考核(Evaluation)
<br>總成績算法 — Homework 40% / Midterm and final Exam. 40% / Projects/ 20%
<br>Homework 遲交一天扣該次 homework 成績10%，遲交三天視同未交。
<br>請勿遲到, 遲到兩次以曠課一次論，曠課一次扣總成績十分，曠課三次以不及格論。
<br>
<br>五、可連結之網頁位址
<br>NTHU E-Learning System
<br>http://alpha.life.nthu.edu.tw/
<br>
<br>六、預定教學進度
<br>
<br>Date_____ Topics         
<br>-------------------------------------------------------------------
<br>楊立威老師
<br>9/14_____Introduction to bioinformatics             	 
<br>_________Mol Biol refresher / Bioinformatics in a nutshell / 
<br>_________dynamics programming I (nucleotides)
<br>9/21_____Dynamics programming II (proteins)
<br>9/28_____教師節 (停課一天)	
<br>10/05____BLAST – Algorithm & hands on 
<br>10/12____Web-based sequence search/comparison tools I
<br>10/19____Web-based sequence search/comparison tools II +
<br>_________concept of systems biology
<br>10/26____Genomics & NGS
<br>11/02____SNP and Genotyping
<br>11/09____Midterm Exam	
<br>-------------------------------------------------------------------
<br>呂平江老師
<br>11/16____全校運動會 (No Class)
<br>11/23____Protein Sequence/Pattern analysi
<br>11/30____Protein Structure Databases	
<br>12/07____Protein Structure Visualization	
<br>12/14____Protein Structure Analysis	
<br>12/21____Protein Structure Modeling & Prediction	
<br>12/28____Structural Comparison /	
<br>1/04_____Molecular Docking	
<br>1/11_____Final Exam
<br>