一、課程說明 (Course Description)

This course is to provide the students who lack basic training in materials science with the fundamental concepts of biomaterials, including three types of biomaterials (metals, ceramics and synthetic and natural macromolecules) and their chemical structure, physical properties, processing and applications. Biocompatibility of materials pertinent to their applications in biomedical engineering is another important issue to be addressed in this course. This includes the interactions of biomaterials with proteins and cells and biomaterial-elicited specific immune responses.

二、指定用書 (Text Books)


三、參考書籍 (References)
1. S. V. Bhat, Biomaterials, Alpha Science, 2nd Ed., 2005.
2. W. Smith, Foundations of Materials Science and Engineering, McGraw-Hill, 2nd Ed., 1993.
3. J. S. Temenoff and A. G. Mikos, Biomaterials: The Intersection of Biology and Materials Science, Pearson, International Edition, 2008.
4. Q. Chen and G. Thouas, Biomaterials: A Basic Introduction, CRC Press, 1st Ed., 2015.
5. C. M. Agrawal, J. L. Ong, M. R. Appleford and G. Mani, Introduction to Biomaterials: Basic Theory with Engineering Applications, Cambridge University Press, 1st Ed., 2014.


四、教學方式 (Teaching Method)

Lectures

五、教學進度 (Syllabus)

Contents
1. Introduction
2. metals
3. Ceramics
4. Polymers
5. Physical and Mechanical Properties of Biomaterials
6. Protein Interactions with Biomaterials
7. Cell Interactions with Biomaterials
8. Biomaterial Implantation and Acute Inflammation
9. Wound Healing and the Presence of Biomaterials
10. Immune Response to Biomaterials
11. Biomaterials and Thrombosis

六、成績考核(Evaluation)

45% Midterm Exam
45% Final Exam
10% On-class discussion
100% Total


七、可連結之網頁位址