一、課程說明(Course Desc<x>ription) 
<br>The course of Vaccine Engineering or Vaccinology contains the principles and 
<br>practices of vaccinology, the basics of immunization sciences including the 
<br>modes of action for adjuvants, the antigen discovery, engineering, and 
<br>presentation, and the vaccine delivery systems.
<br>
<br>疫苗工程學(vaccinology)課程內容包括對疫苗的原理與實用技術，免疫科學如佐劑，抗原與疫苗遞
<br>送技術之發展． 
<br>
<br>
<br>二、指定用書(Text Books) 
<br>1. Vaccinology: Principles and Practice, Edited by Marrow, Sheikh, Schmidt, 
<br>Davies, Wiley-Blackwell, 2012.
<br>2. Janeway's Immunobiology, 9th edition, Kenneth Murphy and Casey Weaver, 
<br>2017.
<br>
<br>三、參考書籍(References) 
<br>
<br>四、教學方式(Teaching Method) 
<br>五、教學進度(Syllabus) 
<br>
<br>Part 1. Introduction- Concept and Scope of Modern Vaccines
<br>1. Concept and Scope of Modern Vaccines
<br>- Chap 16 Manipulation of the Immune response-Using the immune response to 
<br>attack tumors, Fighting infectious diseases with vaccination (Janeway's)
<br>
<br>Part 2. Principles of Vaccine Design
<br>2. Strategies to stimulate innate immunity for designing effective vaccine 
<br>adjuvants
<br>- Chap 3 The induced Responses of Innate Immunity (Janeway's)
<br>3. Antigen processing and presentation by MHC class I, II, and nonclassical 
<br>molecules
<br>- Chap 6 Antigen Presentation to T lymphocytes (Janeway's)
<br>4. Understanding the mucosal immune system for better mucosal vaccine design
<br>- Chap 12. The Mucosal Immune System (Janeway's)
<br>5. immunological memory: T cells in human
<br>6. Immunological memory: B cells
<br>- Chap 11. Integrated Dynamics of Innate and Adaptive Immunity- 
<br>               Immunological memory (Janeway's)
<br>
<br>Part 3. Antigen Discovery
<br>Part 4. Antigen Engineering
<br>Part 5.Delivery Systems
<br>Part 6. Regulatory Considerations
<br>
<br>六、成績考核(Evaluation) 
<br>A series of written exams (100%)