一、課程說明(Course Description)

免疫系統是一高度多樣化之防禦系統藉以清除致病性微生物及癌細胞。在這防禦系統中,各類特定
功能的細胞與分子密切合作形成一動態的網絡,其複雜的程度不下於神經系統。近幾年,由於免疫
學上多項突破性發現,使得這門科學漸趨成熟,而與神經科學並列為二十一世紀之顯學。無庸至疑
地,免疫學是一不可缺少的生命科學課程。

本課程歡迎對免疫學有興趣的大學部學生及研究生修習。亦至誠歡迎非生科系院同學選修。課程內
容包括探討基本的免疫學現象及機制,簡言之,即是分子辨識(molecular recognition) 與反
應 (response);以及免疫學在生物醫學及產業的應用,如免疫療法(immunotherapy)、單株抗
體、疫苗設計、生物感應器(biosensors)等。本課程由專業免疫學家張老師負責設計與主要講
授。

二、指定用書(Text Books)

Parham's The Immune System, 4th Edition, 2015; Garland Science; ed: Peter
Parham

三、參考書籍(References)

Janeway's Immunobiology, 9th Edition, 2016; Garland Science; ed: Kenneth
Murphy

Scientific journal articles.

Kuby Immunology, 6th Edition, 2007; W. H. Freeman and Company; eds: Thomas
Kindt, Richard Goldsby, Barbara Osborne.

四、教學方式(Teaching Method)

Lectures/影片觀賞與討論/網路平台; 新知介紹; 分組報告

五、暫定教學進度(Tentative Syllabus)
9/11 Introduction and grouping
9/18 Basic Concepts in Immunology and Innate Immunity
9/25 Complement and Antigen Recognition by B-cell receptors
10/2 Antigen Recognition by T-cell receptors and MHC/Antigen Presentation to
T Lymphocytes
10/9 國慶日彈性放假
10/16 The Generation of Lymphocyte Antigen Receptors
10/23 Signaling Through Immune System Receptors
10/30 The Development and Survival of Lymphocytes
11/6 Mid-term Exam
11/13 T Cell-Mediated Immunity
11/20 The Humoral Immune Response
11/27 Dynamics of Adaptive Immunity
12/4 Mucosal Immunity and Vaccines
12/11 Cancer and the Immune System
12/18 Allergy, Hypersensitivity and Autoimmunity
12/25 Group presentation
1/1 開國紀念日放假
1/8 Group presentation

六、成績考核(Evaluation)
Tentative:
Exam 30%
Oral presentation 30%
Homework 30%
Attendance 10%

七、可連結之網頁位址

iLMS http://lms.nthu.edu.tw