Brief Course Desc<x>ription
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<br>Organome<x>tallic chemistry is a very promising area in the development of modern 
<br>organic synthesis. To understand the basic principles of organome<x>tallic 
<br>chemistry, course content focuses on reaction rules, catalytic mechanisms, 
<br>research methods and their application in chemical synthesis of me<x>tal organic 
<br>chemistry via the various example of organome<x>tallics. The course content is 
<br>planned for two topics. The first is a basic introduction of organome<x>tallics, 
<br>which includes the counting of electrons for organome<x>tallic structure and their 
<br>bonding, discussing the role of me<x>tals and ligands, and the theory of 
<br>organome<x>tallic reaction mechanism. The second topic is to introduce examples of 
<br>various me<x>tal complex used in organic synthesis. We can understand the reaction 
<br>mechanism, master the synthetic technology and understand a variety of 
<br>cyclization reactions and asymmetric stereochemistry via the applications of 
<br>organome<x>tallic synthesis with main group elements.
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<br>Detailed Course Syllabus
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<br>Organome<x>tallic chemistry, course planning is as follows:
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<br>(1) Introduction of Organome<x>tallic Chemistry
<br>  (a) Organome<x>tallic structures, energy levels of d-orbital, electron counting 
<br>and the 18 electron rule.
<br>  (b) Discussion of me<x>tal-ligand bonding: alkyne, olefin, carbon monoxide, 
<br>methylene, benzene and cyclopentadiene.
<br>  (c) Mechanism and theory of organome<x>tallics: oxidative addition, reductive 
<br>elimination and migration & insertion reactions.
<br>  (d) Electrophilic & nucleophilic reaction and carbon-carbon bond formation.
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<br>(2) Organome<x>tallics in organic synthesis.
<br>  (a)Organome<x>tallic synthesis and applications with main group and halogen.
<br>  (b)Organome<x>tallic synthesis with σ bond and Cu, Zn, Cr.
<br>  (c)Transition me<x>tals in catalytic coupling reaction.
<br>  (d) Catalytic reaction of σ bond. 
<br>  (e) Catalytic reaction of π system: alkyne, propenyl and ethynyl group.
<br>  (f) Cyclization reaction and asymmetric stereochemistry.
<br>  (g) Asymmetric catalytic reaction.
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