一、課程說明(Course Desc<x>ription)
<br>    This course is a continuation of Tumor Biology I and/or II (LSMC575300 
<br>and/or LSMC575400). Please make sure that you did take the prerequisite prior 
<br>to join this class.
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<br>    In 1863, Prof. Virchow postulated that chronic irritation and previous 
<br>injuries are a precondition for tumorigenesis. In 1986, Dr. Dvorak recognized 
<br>that the composition of the tumor stroma strongly resembles the granulation 
<br>tissue of healing skin wounds and postulated that "tumors are wounds that do 
<br>not heal“ in NEJM. In 2011, Dr. Weinberg concluded that in addition to cancer 
<br>cells, tumors exhibit another dimension of complexity: they contain a 
<br>repertoire of recruited, ostensibly normal cells that contribute to the 
<br>acquisition of hallmark traits by creating the "tumor microenvironment“. 
<br>Rather than a single cell disease, the system involved in aberrant wounding 
<br>and chronic inflammation is also responsible for patients poor outcome. 
<br>Although the advances in science are changing what we know about cancer 
<br>complexity, there is still no efficient method to differentiate the cancer 
<br>attributes between patients. We will discuss the issue in the class. 
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<br>二、指定用書(Text Books)
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<br>    Current cancers review and articles.
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<br>三、參考書籍(References)
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<br>四、教學方式(Teaching Method)
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<br>五、教學進度(Syllabus)
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<br>六、成績考核(Evaluation)
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<br>    1. attendance and participation
<br>    2. final report
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<br>七、可連結之網頁位址
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