一、課程說明(Course Desc<x>ription)
<br>The course contains the principles of innate immunity, cellular and humoral 
<br>adaptive immunity, dynamic of adaptive immune system and mucosal immunity, and 
<br>the applications to vaccine development such as adjuvants, antigen character 
<br>and epitope analysis, and the new generations of vaccine development such as 
<br>viral and bacterial vector vaccines, recombinant protein vaccines, DNA 
<br>vaccines as well as new therapeutic vaccines against neoplasm, loss 
<br>individuality, and organ or tissue damages.
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<br>疫苗與免疫科學課程內容主要講述先天性免疫,T細胞與體液免疫系統,免疫動態系統與黏膜免
<br>疫理,同時就疫苗發展與佐劑的應用，抗原特性與新疫苗技術發展如活毒疫苗，次單元與類病毒顆
<br>粒疫苗，病毒與細菌載體疫苗與DNA疫苗加以介紹．同時除了針對預防性疫苗外也包括新發展的治
<br>療性疫苗應用於癌症,異體移植與自體免疫疾病, …等． 
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<br>二、指定用書(Text Books)
<br>Janeway's Immunobiology, 9th edition, Kenneth Murphy, 2016 
<br>Chapter 3 The Induced Response of Innate Immunity
<br>Chapter 6 Antigen Presentation to T lymphocytes
<br>Chapter 9 T cell-mediated immunity 
<br>Chapter 10 The humoral immune response 
<br>Chapter 11 Integrated dynamics aof innate and adaptive immunity 
<br>Chapter 12 The mucosal immune system
<br>Chapter 16 Manipulation of the immune Response: 
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<br>三、參考書籍(References)
<br>Vaccinology: principle and practice, Morrow, Sheikh, Schmidt, Davies, Wiley-
<br>Blackwell 2012 
<br>Part 1 Introduction
<br>Part 2 Principles of vaccine design
<br>Part 3 Antigen discovery
<br>Part 4 Antigen engineering
<br>Part 5 Delivery systems
<br>Part 6 Regulatory Consideration
<br>Part 7 Evaluating vaccine efficacy
<br>Part 8 Implementing immunizations/therapies
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<br>四、教學方式(Teaching Method)
<br>English lectures
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<br>五、教學進度(Syllabus)
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<br>Chapter 3 The Induced Response of Innate Immunity
<br>Chapter 6 Antigen Presentation to T lymphocytes
<br>Chapter 9 T cell-mediated immunity 
<br>Chapter 10 The humoral immune response 
<br>Chapter 11 Integrated dynamics aof innate and adaptive immunity 
<br>Chapter 12 The mucosal immune system
<br>Chapter 16 Manipulation of the immune Response: 
<br>           Series I: Prophylactic vaccines against infections
<br>           Series II: Therapeutic vaccines attacking tumors
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<br>六、成績考核(Evaluation)
<br>Quiz, mid-term and final close-book exam 
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<br>七、可連結之網頁位址