This course is offered in English.
<br>本課程採英文授課.
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<br>Parts of the contents require basic knowledge in Biochemistry.
<br>部分內容需具有生科系本科生大二生化基礎
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<br> 一、課程說明(Course Desc<x>ription)
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<br>In this course, we will introduce essential servers, databa<x>ses and online 
<br>tools in Bioinformatics. We will also conduct hand-on exercises in 
<br>functional genomics and protein analyses.
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<br>本課程兼重學理與實作，藉由習題與範例，使學員能熟悉網路上各種生物資訊之取得及工具應
<br>用，並針對各種常用生物資料庫作概略性的介紹，包括 NCBI, Protein Data Bank (PDB)、 
<br>KEGG、ExPasy 等生物資料庫。 課程中將連線上網，實際操作、演練各種輔助軟體 
<br>(Browser, viewer, molecular displa<x>yer...)。
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<br>二、參考書籍(References)
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<br>1. Bioinformatics: a practical guide to the analysis of genes and proteins
<br>Third Edition -- Gene Module
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<br>三、教學方式(Teaching Method)
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<br>Lectures and hand-on training will be offered in Life Science computer room.
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<br>在電腦教室上課，課堂講解示範與學生實地操做並行。
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<br>四、暫定教學進度(Tentative Syllabus)
<br>1. Introduction to Bioinformatics:
<br>2. Information retrieval from biological databa<x>se
<br>3. DNA Databa<x>se - GeneBank
<br>4. DNA Sequence Analysis
<br>5. Protein Sequence Databa<x>se - SwissProt
<br>6. Protein Sequence Analysis
<br>7. Protein Structure Databa<x>se - PDB
<br>8. Protein Structure Analysis
<br>9. Protein Structure Comparison
<br>10. Protein Structure Modelling
<br>11. Protein Docking
<br>12. Structure ba<x>sed Drug Design 
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<br>五、成績考核(Evaluation)
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<br>Grading policy - Homework 50% / Midterm and final Exam. 30% / Projects 20% 
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<br>10% credit will be deducted for late homework. Homework submission shall be 
<br>be delayed for more than 3 days. 
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<br>Do not be late for the class. Two counts of late arrival will be marked as 1  
<br>absence (10% credit deduction for the final score.) Three absences will 
<br>result in a "F" of the final grade.
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<br>上課時間 — 請勿遲到 
<br>遲到兩次以曠課一次論，曠課一次扣總成績十分，曠課三次以不及格論。 
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<br>六、可連結之網頁位址 (li<x>nks)
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<br>NTHU E-Learning System:  http://lms.nthu.edu.tw/
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<br>NTHU LS Alpha server: http://alpha.life.nthu.edu.tw/
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