This course is offered in English.

Parts of the contents require basic knowledge in Biochemistry.

一、課程說明(Course Description)

In this course, we will introduce essential servers, databases and online
tools in Bioinformatics. We will also conduct hand-on exercises in
functional genomics and protein analyses.

用,並針對各種常用生物資料庫作概略性的介紹,包括 NCBI, Protein Data Bank (PDB)、
KEGG、ExPasy 等生物資料庫。 課程中將連線上網,實際操作、演練各種輔助軟體
(Browser, viewer, molecular displayer...)。


1. Bioinformatics: a practical guide to the analysis of genes and proteins
Third Edition -- Gene Module

三、教學方式(Teaching Method)

Lectures and hand-on training will be offered in Life Science computer room.


四、暫定教學進度(Tentative Syllabus)
1. Introduction to Bioinformatics:
2. Information retrieval from biological database
3. DNA Database - GeneBank
4. DNA Sequence Analysis
5. Protein Sequence Database - SwissProt
6. Protein Sequence Analysis
7. Protein Structure Database - PDB
8. Protein Structure Analysis
9. Protein Structure Comparison
10. Protein Structure Modelling
11. Protein Docking
12. Structure based Drug Design


Grading policy - Homework 50% / Midterm and final Exam. 30% / Projects 20%

10% credit will be deducted for late homework. Homework submission shall be
be delayed for more than 3 days.

Do not be late for the class. Two counts of late arrival will be marked as 1
absence (10% credit deduction for the final score.) Three absences will
result in a "F" of the final grade.

上課時間 — 請勿遲到

六、可連結之網頁位址 (links)

NTHU E-Learning System:

NTHU LS Alpha server: