一、課程說明(Course Desc<x>ription)
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<br>免疫系統是一專一且高度多樣化之個體防禦系統，在這防禦系統中，各類特定功能的細胞與分子密切合作形成一動態的網絡，藉以清除致病性微生物與癌細胞。然而免疫系統的失調以及微生物與癌細胞的反制亦造成感染症、癌症、及自體免疫疾病的惡化，吾人該如何設計有效的免疫療法及疫苗? 近年來，由於免疫學研究有多項突破性的進展，使得這門科學漸趨成熟，已成為二十一世紀之顯學。無庸至疑地，免疫學是一不可或缺的生命科學課程。
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<br>本課程歡迎對免疫學有興趣的大學部學生及研究生修習。亦歡迎非生科系院同學選修。課程內容包括探討基本的免疫學現象及機制，簡言之，即是分子辨識(molecular recognition) 與反應 (response)，以及免疫學在生物醫學及產業的應用，如免疫療法(immunotherapy)、單株抗體、疫苗設計、生物感應器(biosensors)等。本課程由張老師開設。
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<br>二、指定用書(Text Books)
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<br>Parham's The Immune System, 4th Edition, 2015; Garland Science; ed: Peter 
<br>Parham 
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<br>三、參考書籍(References)
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<br>Janeway's Immunobiology, 9th Edition, 2016; Garland Science; ed: Kenneth 
<br>Murphy 
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<br>Scientific journal articles.
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<br>Kuby Immunology, 6th Edition, 2007; W. H. Freeman and Company; eds: Thomas 
<br>Kindt, Richard Goldsby, Barbara Osborne. 
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<br>四、教學方式(Teaching Method)
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<br>Lectures/影片觀賞與討論/實例討論; 新知介紹; 分組報告。
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<br>五、暫定教學進度(Tentative Syllabus)
<br>9/14 Introduction and grouping
<br>9/21 Elements of the Immune System and Innate Immunity (complements) 
<br>9/28 教師節(停課一天) 
<br>10/5 Innate Immunity (Toll-like receptors and natural killer cells)  
<br>10/12 Antibody structure and the generation of B-cell diversity
<br>10/19 Antigen Recognition by T cell receptors and Antigen Presentation to 
<br>T Lymphocytes
<br>10/26 MHC and transplantation of tissues and organs
<br>11/2  Signaling Through Immune System Receptors
<br>11/9  The Development and Survival of Lymphocytes 
<br>11/16 Mid-term Exam
<br>11/23 T Cell- and B cell-Mediated Immunity
<br>11/30 Infectious diseases and vaccines (I)
<br>12/7 Infectious diseases and vaccines (II)  
<br>12/14 Cancer and the Immune System
<br>12/21 Cancer Immunotherapy and Clinical Trials
<br>12/28 Allergy and Autoimmune diseases
<br>1/4  Group presentation
<br>1/11 Group presentation
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<br>六、成績考核(Evaluation)
<br>暫定:
<br>Exam 30%
<br>Oral presentation 30%
<br>Homework 30%
<br>Attendance and asking questions 10%
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<br>七、可連結之網頁位址
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<br>iLMS http://lms.nthu.edu.tw
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