一、Course Description

1. This course provides a general overview of recent advancement of medical
biotechnology.
2. Major medical biotechnology fields including drugs, vaccine, medical devices,
and diagnostics will be introduced.
3. This course is of advanced level and is more suitable for students with strong
biochemistry background.
4. This course will conduct intensive discussion in the classroom.
5. In addition to technology, business and ethic aspects will be included.

二、Text Books
No textbook will be assigned.

三、References

Selected articles from biotechnology journal will be assigned.
Scientific American
Nature Biotechnology
Trends in Biotechnology
Current Opinions in Biotechnology
etc.


四、Teaching Method

Lectures, Discussion, student presentation

五、Syllabus

Topics to be discussed in the class
1、Biotechnology: current status and perspective
2. Application of genomics, proteomics, metabolomics, microbiomics, and other

omics in medical biotechnology
3. [Protein drugs -1] Protein and antibody drug engineering
4. [Protein drugs -2] Recombinant protein production
5. [Small molecule drugs -1] Herbal medicine and natural compounds as drug
6. [Small molecule drugs -2] Nucleoside analogs, antimicrobials, others
5. [Vaccines]
7. [Nucleic acid drug2 -1] DNA and gene therapy
8. [Nucleic acid drugs -2] mRNA, siRNA, and other RNA-based drugs.
9. Drugs/vaccines formulation and delivery
10.Problem-based discussion (1)
11. [Diagnostics -1] Chemistry and physics of in vitro diagnostics
12. [Diagnostics -2] Biochips/bioMEMS /biosensors/imaging
13. [Regenerative medicine -1] Biomaterials
14 [Regenerative medicine -2] Stem cells and Tissue engineering
15. Medical devices
16. Problem-based discussion (2)



六、Evaluation

Oral presentation 10%
Term paper 10%
Class participation 40%
Examination 40%


七、Website

Please consult the university iLMS E-learning platform.