一、課程說明(Course Desc<x>ription)
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<br>Transc<x>ription Factor Forkhead Box (Fox) protein family members regulate 
<br>transc<x>riptional network of genes control multiple cell physiology, such as 
<br>development, cancer and other diseases.  This course aims to help students 
<br>understand the molecular mechanisms and biological roles of FoxM1 and FoxO by 
<br>covering the following issues: 1)Biological functions of Forkhead box family 
<br>transc<x>ription factors; 2) Fox proteins transc<x>riptional regulate cell cycle 
<br>progression; 3) Fox target genes and regulatory signal pathways; 4) Fox proteins 
<br>in mouse embryonic development; 5) Fox proteins in cancer biology; 6) Cross 
<br>talks between Fox proteins and related diseases.
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<br>二、指定用書(Text Book)
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<br>三、參考書籍(References)
<br>Selected papers
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<br>四、教學方式
<br>Lecture/ Seminar /Discussion
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<br>五、教學進度
<br>Week1   Introduction to Fox transc<x>ription factors
<br>Week2   Discovery of Foxm1 and liver transc<x>ription factors
<br>Week3   Molecular analysis of Foxm1 protein
<br>Week4   Fox family in cell cycle regulation  
<br>Week5   Holiday 
<br>Week6   Fox family, SCF and Protein degradation
<br>Week7   Fox family in lung and liver cancers
<br>Week8	Fox family in ovary and colorectal cancers 
<br>Week9	Fox family in lung development and maturation
<br>Week10	Fox O and FoxM1 in oxidative stress response
<br>Week11	Fox family in embryonic development
<br>Week12  Aging Foxes
<br>Week13	Fox family in injury-repair process
<br>Week14	Fox family in stem cells
<br>Week15  The crosstalk between FoxO and FoxM1
<br>Week16  Fox in cell me<x>tabolism and mitochondria autophagy
<br>Week17	Overview of the other Fox family proteins 
<br>Week18  Final exam
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<br>六、成績考核
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<br>Attendance 10%
<br>Discussion/Seminar 60%
<br>Mid-term and Final report 30%
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<br>七、講義位址
<br>    https://eeclass.nthu.edu.tw/