一、課程說明(Course Desc<x>ription)
<br>免疫系統是一專一且高度多樣化之個體防禦系統，在這防禦系統中，各類特定功能的細胞與分子密切合
<br>作
<br>形成一動態的網絡，藉以清除致病性微生物與癌細胞。然而免疫系統的失調以及微生物與癌細胞的反制
<br>亦
<br>造成感染症、癌症、及自體免疫疾病的惡化，吾人該如何設計有效的免疫療法及疫苗? 近年來，由於
<br>免疫
<br>學研究有多項突破性的進展，使得這門科學漸趨成熟，已成為二十一世紀之顯學。無庸至疑地，免疫學
<br>是
<br>一不可或缺的生命科學課程。
<br>
<br>本課程歡迎對免疫學有興趣的大學部學生及研究生修習。亦歡迎非生科系院同學選修。課程內容包括探
<br>討
<br>基本的免疫學現象及機制，簡言之，即是分子辨識(molecular recognition) 與反應 
<br>(response)，以
<br>及免疫學在生物醫學及產業的應用，如免疫療法(immunotherapy)、單株抗體、疫苗設計、生物感應
<br>器
<br>(biosensors)等。
<br>
<br>二、指定用書(Text Books)
<br>Parham's The Immune System, 4th Edition, 2015; Garland Science; ed: Peter
<br>Parham
<br>
<br>三、參考書籍(References)
<br>
<br>Kuby Immunology, 9th Edition, 2019; W. H. Freeman and Company; eds: Thomas
<br>Kindt, Richard Goldsby, Barbara Osborne.
<br>
<br>Cellular and Molecular Immunology, 7th Edition, 2012; Elsevier Inc., eds: Abul K. 
<br>Abbas, Andrew H. Lichtman, Shiv Pillai.
<br>
<br>Basic Immunology, 6th Edition, 2019; Elsecier Inc., ed: Abul Abbas Andrew H. 
<br>Lichtman Shiv Pillai
<br>
<br>
<br>Janeway's Immunobiology, 9th Edition, 2016; Garland Science; ed: Kenneth
<br>MurphyScientific journal articles.
<br>
<br>
<br>四、教學方式(Teaching Method)
<br>Lectures/影片觀賞與討論/實例討論; 新知介紹。
<br>
<br>五、暫定教學進度(Tentative Syllabus)
<br>1 9/13	Overview of immune system: Cells, organs, microenvironments of immune 
<br>system
<br>2 9/20  中秋節彈性放假
<br>3 9/27	Innate immunity: The first line of defense
<br>4 10/4	Antibody Structure and the Generation of B-Cell Diversity
<br>5 10/11 國慶日補假
<br>6 10/18	Antigen Recognition by T Lymphocytes
<br>7 10/25	The Development of B Lymphocytes
<br>8 11/1	The Development of T Lymphocytes
<br>9 11/8	Mid-exam
<br>10 11/15	T Cell-Mediated Immunity
<br>11 11/22	Immunity Mediated by B Cells and Antibodies
<br>12 11/29	Preventing Infection at Mucosal Surfaces
<br>13 12/6 	Immunological Memory and Vaccination
<br>14 12/13	Failures of the Body’s Defenses
<br>15 12/20	Allergy and Autoimmune diseases 
<br>16 12/27	Disruption of Healthy Tissue by the Adaptive Immune Response
<br>17 1/3	        Cancer and the Immune system
<br>18 1/10	        Final-exam
<br>
<br>六、成績考核(Evaluation)
<br>暫定:
<br>Exam 70% (mid 30%, final 40%)
<br>Homework 15%
<br>Attendance and asking questions 15%