課程名稱：分子生醫基礎
<br>英文課名：Introduction to Molecular biomedicine
<br>課程編號：BMES 520100; 學 分 數：3
<br>地點時間：醫環系101R / Wednesday Morning  2nd, 3rd, 4th class (9:20-12:00)
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<br>授課教師：莊淳宇 / Room 217 / ext 34229 / cychuang@mx.nthu.edu.tw
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<br>講    義： eeclass (https://eeclass.nthu.edu.tw/)
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<br>Purpose
<br>This course consists of lecture topics, concept of lab technique and periodic 
<br>examinations for basic molecular biology and medicine. The students are expected 
<br>to develop a comprehensive understanding of molecular biology and to be able to 
<br>critically select necessary techniques in their own research. This course is 
<br>designed for the graduate and advanced undergraduate students interested in 
<br>molecular biomedicine even though without biology background.
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<br>Performance: Lecture, Presentation, Examination
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<br>Schedule
<br>Lecture Topic [Lab Hint]
<br>Introduction	
<br>Ch. 3, 4: DNA Nature [Ch. 21: Purification of nucleic acid]
<br>Ch. 5: DNA Replication [Ch. 21: Detection of nucleic acid] 
<br>Ch. 6: Gene Transc<x>ription	 
<br>Ch. 13: Mutations [Ch. 23: PCR]
<br>Ch. 14: Repair	 
<br>Ch. 22, 16: Recombinant DNA [Ch. 22: Restriction Endonucleases]	 
<br>Ch. 9: Transc<x>ription in prokaryotes
<br>Ch. 10: Transc<x>ription in eukaryotes [Ch. 25: Analysis of gene ex<x>pression] 
<br>Ch. 11: Regulation of RNA level	 
<br>Ch. 12: RNA processing 	 
<br>Ch. 7, 8: Protein synthesis (Translation)	 
<br>Ch. 24, 26: Genomics, Proteomics	 	 
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<br>Text Book
<br>David P. Clark. Molecular Biology, Academic Cell, 2nd edition, 2012 (ISBN-10: 
<br>0123785944).
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<br>Reference
<br>1. James D. Watson. Molecular Biology of the Gene. Pearson.
<br>2. Robert F Weaver. Molecular Biology. McGraw-Hill Education.
<br>3.Roger L Miesfeld. Applied Molecular Genetics. Wiley-Liss, A John Wiley & Sons, 
<br>Inc., 
<br>Publication.
<br>4. Dennis W Ross. Introduction to Molecular Medicine. Spring.
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<br>Presentation: 5 groups 
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<br>Grades: Midterm exam: 35%; Final exam: 35%, Presentation: 30%
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