一、課程說明(Course Desc<x>ription)
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<br>Systems biology is a discipline that integrates biochemistry, cell biology, 
<br>computer science, and systems engineering to provide a holistic view on 
<br>biological functions and structures. The genomic revolution of high-
<br>throughput techniques has opened up systematic investigations and 
<br>engineering designs for various life forms. System biology entails synthetic 
<br>biology and creates many emerging applications in energy, pharmaceuticals, 
<br>bio-materials, foods, ecosystem protection, etc. through engineering 
<br>principles. This course will discuss the system-level models of various 
<br>basic biological process, analysis of experimental and literature data, and 
<br>deduce interesting theoretical insight.
<br>Students will need basic understanding of linear algebra, probability, and 
<br>control theory. No prerequisite of biology courses is essential to take this 
<br>course. 
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<br>課程內容
<br>1.Introduction (Cell Biology)
<br>2.Modeling of Biochemical Systems (Basic Mathematics and Control Theory)
<br>3.Specific Biochemical Systems
<br>4.Model Fitting
<br>5.Analysis of High-throughput Data
<br>6.Gene ex<x>pression Models
<br>7.Stochastic Systems and Variability (Statistics and Stochastic Processes)
<br>8.Network Structures, Dynamics, and Function
<br>9.Optimality and Evolution
<br>10.Experimental Techniques in Molecular Biology
<br>11.Databa<x>ses
<br>12.Modeling Tools
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<br>二、指定用書(Text Books)
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<br>   教科書  : Lecture Notes (自編講義)
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<br>三、參考書籍(References)
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<br>1.Systems Biology : A Textbook
<br>  Edda Klipp, Wolfram Liebermeister, Christoph Wierling, Axel Kowald, Hans   
<br>  Lehrach, Ralf Herwig, August 2009, Wiley
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<br>2. Systems Biology and Synthetic Biology
<br>   Pengcheng Fu, Sven Panke, April 2009, Wiley
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<br>3.An Introduction to Systems Biology : Design Principles of Biological 
<br>Circuits
<br>  Uri Alon, July 2006, Chapman and Hall/CRC
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<br>四、教學方式(Teaching Method)
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<br>    投影片教學
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<br>五、教學進度(Syllabus)
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<br>    一星期一單元為原則
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<br>六、成績考核(Evaluation)
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<br>    期中考及期末考 50% , 作業 50% 
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<br>七、可連結之網頁位址
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<br>    遠距會議連結:https://meet.google.com/vcc-wykt-bba
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