一、課程說明(Course Description)
Introducing the basic concepts of molecular biophysics. Including the
following topics:
1.Macromolecular structure and Dynamics
2.Methods of Separation and Characterizations
3.Theory of X-ray Diffraction
4.Solving Macromolecular Structure by X-ray Diffraction
5.Cryo Electron Microbiology
6.Single-Molecule Methods
7.NMR
8.Mass and CD Spectroscopy.
9.Chemical Equilibria - Ligand Binding
10.Structural Stability and Transition


二、指定用書(Text Books)

Molecular Biophysics - Structures in motion
By Michel Daune
Principles of Physical Biochemistry
By Kensal E. van Holde, W. Curtis Johnson and P. Shing Ho

On line course - Getting started in cryo-EM (free via Coursera)
https://www.coursera.org/learn/cryo-em


三、參考書籍(References)


四、教學方式(Teaching Method)

課堂講授


五、教學進度(Syllabus)

根據syllabus之進度


六、成績考核(Evaluation)

三次考試各佔34%


七、可連結之網頁位址