一、課程說明(Course Desc<x>ription)
<br>Focus on the emerging areas of lung epithelial biology and the critical issues 
<br>on normal lung development and diseases. Current subjects of lung research field 
<br>such as interaction of epithelia and stroma, immune interaction, as well as 
<br>regulatory signaling pathways will be introduced and discussed. The course aims 
<br>to help students understand the fundamental and molecular mechanism of health 
<br>and diseased lungs by covering following issues: (1) Lung epithelial development 
<br>(2) lung biology and maintenance of lung function (3) epithelia-mesenchyme 
<br>interaction (4) Acute and chronic pulmonary diseases (5) lung cancer initiation 
<br>and me<x>tastasis (6) normal lung stem cell and lung cancer stem cells (7) lung 
<br>fibrosis. 
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<br>二、指定用書(Text Books)
<br>Selected papers
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<br>三、參考書籍(References)
<br>Selected papers
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<br>四、教學方式(Teaching Method)
<br>Lecture/ Seminar /Discussion
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<br>五、教學進度(Syllabus)
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<br>Week 1 Overview of lung biology 
<br>Week 2 Genetic control of lung development
<br>Week 3 Branch morphogenesis and airway development
<br>Week 4 Surfactant proteins and lipids in lung function
<br>Week 5 Surfactants and Respiratory distress syndrome
<br>Week 6 Epithelial-mesenchymal interrelationships
<br>Week 7 Lung homeostasis
<br>Week 8 Acute lung injury, repair and regeneration
<br>Week 9 Stem cells and epithelial cell plasticity
<br>Week 10 pulmonary fibrosis  
<br>Week 11 Lung inflammation and asthma 
<br>Week 12 Overview of lung cancers 
<br>Week 13 Transc<x>riptional regulation in lung cancer initiation
<br>Week 14 Transc<x>riptional regulation in lung cancer me<x>tastasis
<br>Week 15 Lung cancer mouse models 
<br>Week 16 Lung cancer stem cell
<br>Week 17 Lung cancer drug resistance
<br>Week 18 Final report
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<br>六、成績考核(Evaluation)
<br>Attendance 20%
<br>Discussion/Seminar 60%
<br>Final report 20%
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