Molecular and Cellular Biology III
一、課程說明 (Course Description)
本課程為分子與細胞生物學之延續課程,本課程共分三部份,第一部份涵蓋基因轉譯為蛋白質之
機制。第二部份涵蓋基因轉錄後之修飾機制。第三部份涵蓋DNA replication,
recombination
and transposition.

二、指定用書 (Text Books)
Molecular Biology by R. F. Weaver 2011. 5th edition. Publisher: WCB/McGraw
Hill

三、參考書籍 (References)
1. Molecular Cell Biology, by Lodish et al. 2003. Publisher: W. H. Freeman
and
Company.
2. Molecular biology of the gene by Watson et al. 2004, Fifth edition.
Publisher:
Benjamin cummings
3. Recent papers related to the chapters in course.

四、教學方式 (Teaching Method)
以指定教科書為主,討論各topic 之研究方法、結論及其在分子生物學上之重要性。預期學生除
結論外,也能瞭解現今之研究方向及實驗之方法。

五、教學進度 (Syllabus)
See the attached pdf files in eeclass

六、成績考核(Evaluation)
The grade is the average of three examinations.
助教:
TBA
助教課業諮詢時間: 另行公布

七、可連結之網頁位址
參考書籍置於生科系圖書館,學生可向圖書館小姐借閱。
http://www.life.nthu.edu.tw/~labcwy/teaching.html

11120LS 340200分子與細胞生物學三(Molecular and Cellular Biology III)
2023 Spring T5F5F6
Textbook: 5th edition, Molecular Biology, by Robert F. Weaver

Date Chapter and Topics Lecturer
2/14 T 13 chromatin structure and its effect on transcription 王翊青
2/17 F 13 chromatin structure and its effect on transcription 王翊青
2/21 T 14 RNA processing I: splicing 王翊青
2/24 F 梅竹賽(停課)
2/28 T 和平紀念日(放假)
3/03 F 14 RNA processing I: splicing 王翊青
3/07 T 15 RNA processing II: capping and polyadenylation 王翊青
3/10 F 15 RNA processing II: capping and polyadenylation 王翊青
3/14 T 15 RNA processing II: capping and polyadenylation 王翊青
3/17 F 16 Other post-transcriptional events 王翊青
3/21 T 16 Other post-transcriptional events 王翊青
3/24 F 16 Other post-transcriptional events 王翊青
3/28 T Examination I (lectures 2/14 to 3/24) 王翊青
3/31 F 17 (& 3, 19) ribosome, transfer RNA and messenger 周裕珽
4/04 T 兒童節 (放假)
4/07 F 17 (& 3, 19) ribosome, transfer RNA and messenger 周裕珽
4/11 T 17 (& 3, 19) the mechanism of translation I: initiation 周裕珽
4/14 F 17 (& 3, 19) the mechanism of translation I: initiation 周裕珽
4/18 T 18 (& 19) the genetic code 周裕珽
4/21 F 18 (& 19) the mechanism of translation II: elongation 周裕珽
4/25 T 18 (& 19) the mechanism of translation II: elongation 周裕珽
4/28 F 18 the mechanism of translation II: termination/posttranslation 周裕珽
5/02 T 18 the mechanism of translation II: termination/posttranslation 周裕珽
5/05 F Examination II (lectures 3/31 to 5/05) 周裕珽
5/09 T 20 DNA replication I: mechanism and enzymology 張壯榮
5/12 F 20 DNA replication I: mechanism and enzymology 張壯榮
5/16 T 21 DNA replication II: detailed mechanism 張壯榮
5/19 F 21 DNA replication II: detailed mechanism 張壯榮
5/23 T 21 DNA replication II: detailed mechanism 張壯榮
5/26 F 22 homologous recombination 張壯榮
5/30 T 22 homologous recombination 張壯榮
6/02 F 22 homologous recombination 張壯榮
6/06 T 23 transposition 張壯榮
6/09 F 23 transposition 張壯榮
6/12 M 期末考週 Examination III (lectures 5/09 to 6/09) 張壯榮