一、課程說明(Course Description)

本課程旨在介紹生醫代謝與合成之化學,透過既有之有機化學基礎,加強同學理解生物系統如何以有
機化學之反應機制進行蛋白酵素催化,分子辨識與藥物運作之方式o

二、指定用書(Text Books)

John McMurry and Tadhg Begley, The Organic Chemistry of Biological Pathways,
2005, Roberts and Company Publishers, Englewood, Colorado



三、參考書籍(References)

P. Y. Bruice, Organic Chemistry, 8th ed. 2016, Pearson education, Inc..



四、教學方式(Teaching Method)

Powerpoint
板書

五、教學進度(Syllabus)

Bruice's Organic Chemistry
chap.20 -The Organic Chemistry of Carbohydrates
chap.21- The Organic Chemistry of Amino Acids, Peptides, and Proteins
chap.22- Catalysis in Organic Reactions and in Enzymatic Reactions

John McMurry's Organic Chemistry
chap.1-Common Mechanisms in Biological Chemistry
chap.2-Biomolecules
chap.3-Lipid metabolism
chap.4-Carbohydrate metabolism
chap.5-Amino Acid metabolism
chap.6-Nucleotide metabolism

Special Topic (I): BNCT in Medicinal Chemistry
Special Topic (II): Fluorine-18 labeling for freshly cooked small molecule’s in-
vivo application


六、成績考核(Evaluation)

Coursework will be evaluated using the following weightings:
Term examination: 40%
Final examination: 30%
Oral Presentation: 30%


七、可連結之網頁位址

https://docs.google.com/presentation/d/1QujKKjTMXw6ui94mRiT4V8INzXB8vHeO/edit?
usp=sharing&ouid=100147154822497656824&rtpof=true&sd=true