Time : Wednesday 9:00 AM – 12:00 PM (-12:20pm for Prof Yang’s part) Room: 生科二館
#109

一、課程說明(Course Description)
Date Topics Instructors
1 9/13 Basic math review, Statistical Ensemble, MD simulation I LW Yang
2 9/20 Basic math review, MD simulation II, Protein Folding LW Yang
3 9/27 Introduction of Liquid-Liquid Phase Separation in Biology (LLPS)
HCCheng
4 10/4 Special Seminar on LLPS HCCheng
5 10/11 Principles Governing LLPS HCCheng
6 10/18 Principles of magnetic resonance SC Sue
7 10/25 Parameters derived from NMR SC Sue
8 11/1 Solution molecular behaviors revealed by NMR SC Sue
9 11/8 Mid exam TA
10 11/15 X-ray Diffraction YJ SUN
11 11/22 Solving Macromolecular Structure by X-ray Diffraction YJ SUN
12 11/29 Solving Macromolecular Structure by X-ray Diffraction YJ SUN
13 12/6 Cryo-EM I PCLin
14 12/13 Cryo-EM II PCLin
15 12/20 Data-Driven Structural Predictions LW Yang
16 12/27 Final exam TA



二、指定用書(Text Books)

Molecular Biophysics - Structures in motion
By Michel Daune
Principles of Physical Biochemistry
By Kensal E. van Holde, W. Curtis Johnson and P. Shing Ho

On line course - Getting started in cryo-EM (free via Coursera)
https://www.coursera.org/learn/cryo-em


三、參考書籍(References)


四、教學方式(Teaching Method)

Lecturing


五、教學進度(Syllabus)

According to the aforementioned schedule


六、成績考核(Evaluation)

Midterm 50%, Final 50%


七、可連結之網頁位址