一、課程說明(Course Description)
Chapter 1: Introduction to the History of Drug Development
Chapter 2: Overview of Antimicrobial Peptide Drugs
Chapter 3: Overview of Oncolytic Peptide Drugs
Chapter 4: Overview of Antibody Drugs
Chapter 5: Overview of PDC and ADC Drugs
Chapter 6: From Chemokines to Anti-cancer Drug Development
Chapter 7: Quality by Design for Biopharmaceutical Drugs
Chapter 8: Overview of Small Molecule Drugs
Chapter 9: Overview of Small Molecule Drugs
Chapter 10: Structure-based Drug Design
Chapter 11: Design of Integrin-Specific Drugs for Cancer
Chapter 12: Overview of Small Molecule Drugs
Chapter 13: Overview of FDA Regulations and Strategies
Chapter 14: New Opportunities for Cancer Therapy in Cancer Treatment
Chapter 15: Introduction to International Pharmaceutical Companies
Chapter 16: Final Report
二、指定用書(Text Books)
無
三、參考書籍(References)
"The Organic Chemistry of Drug Design and Drug Action"
By Richard B.Silverman.
"Nature Reviews Drug Discovery"
By Nature Publication Group
四、教學方式(Teaching Method)
課堂講解及實例解說
五、教學進度(Syllabus)
見課程說明
六、成績考核(Evaluation)
以期末考書面及課堂上台報告為主。
七、可連結之網頁位址
http://life.nthu.edu.tw/~labcjw (建構中)
E-mail: jwcheng@life.nthu.edu.tw
八、本課程為16週授課的課程。將於16週內導入目前國際大藥廠在新藥開發上的方向及實例探討,
並會要求上課學生於期末就最新的藥物設計開發案例擇一進行口頭報告。
九、鼓勵學生使用AI搜尋相關藥物設計方向及進展。並和實際發表論文進行比較。