Course Desc<x>ription: Will focus on synthetic skill training and instruction. 
<br>Isolation and purification of final products by column chromatography and/or re-
<br>crystallization. proton, carbon-13, 2-D correlation NMR analysis to characterize 
<br>the structures. 31P NMR will also be taken.
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<br>Text Books: literature references will be give.
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<br>Teaching Method: ppt and pdf presentation about the experiments.
<br>Simple demonstration of Chem Draw and Chem 3D and SciFinder search use.
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<br>Syllabus:
<br>A total of 4-5 experiments will be carried out, which include the followings:
<br>(1) methyl 2-vinylbenzoate: synthesis and spectroscopic 
<br>assignment
<br>(2) diethyl (E)-(2-bromostyryl)phosphonate: synthesis and spectroscopic 
<br>assignment 
<br>(3) methyl (E)-2-hydroxy-4-phenylbut-3-enoate: synthesis and spectroscopic 
<br>assignment
<br>(4) 1,2-diphenylcyclopropan-1-ol: synthesis and spectroscopic assignment
<br>(5) 4,6-bis((4S,5S)-4,5-diphenyl-4,5-dihydrooxazol-2-yl)dibenzo[b,d]furan: 
<br>synthesis and spectroscopic assignment
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<br>Nucleophilic addition, acyl substitution, nucleophilic substitution, Michael type 
<br>conjugate addition, and Claisen condensation reactions will be covered.
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<br>Their synthetic steps are attached in a separate pdf file.
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<br>Evaluation:
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<br>Experimental skills: 60%
<br>Product yield: 40%
<br>Assignment: 100%.
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<br>Total 200 points for each experiments.
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<br>本課程無涉及AI使用
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