Course: 生醫微熱流 Thermo-fluidics in Bio-MEMS
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<br>When: 112年度2nd semester, Wed 9:00-12:00
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<br>Course Desc<x>ription:
<br>Microfluidics is rapidly emerging as an enabling technology, with applications 
<br>ranging from unmanned aerial vehicles to biomedical applications to drug discovery 
<br>and delivery. Given the importance of micro/nano mechanical and fluidic phenomena, 
<br>it is necessary to understand the fluid mechanics, heat and mass transfer, 
<br>chemistry, biochemistry and engineering principles on which the design of devices 
<br>is ba<x>sed. These courses are essential in understanding the behavior of fluid 
<br>flow 
<br>(droplet) through nano/micro scales for bio-applications.
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<br>Handouts: may be downloaded by the student.
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<br>Textbook:
<br>1.	“Fundamentals and applications of Microfluidics”, N.-T. Nguyen and S. T. 
<br>Wereley, Artech House, 2nd edition, 2008. 
<br>2.	“Introduction to BioMEMS”, Albert Folch, CRC press, 2012.
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<br>Textbook (reference):
<br>1.	“Micro- and Nanoscale Fluid Mechanics”, Brian J. Kirby, Cambridge, 2010. 
<br>2.	“Fluid Power with Applications”, Anthony Esposito, 5th Edition, Prentice 
<br>Hall, 2000.
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<br>Assignments and Grading (subject to revision):
<br>◆ Class participation: 10%
<br>◆ Report: 10%
<br>◆ Midterm exam: 30%
<br>◆ Final presentation (or final exam): 50%
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<br>Contact: 森川響二朗 助理教授 / Kyojiro Morikawa, Assistant Professor 
<br>(morikawa@pme.nthu.edu.tw)
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<br>Contents:
<br>1.	Introduction to BioMEMS 
<br>2.	Introduction to microfluidics – basic principles
<br>3.	Introduction to microfluidics – applications
<br>4.	Microfluidic device fabrication – fabrication method
<br>5.	Microfluidic device fabrication – material (silicon, glass, polymers …)
<br>6.	Microfluidic device fabrication – summary
<br>7.	Flow control method – pump
<br>8.	Flow control method – valve
<br>9.	Surface modification and patterning – method
<br>10.	Surface modification and patterning – application (cell, electrode, 
<br>chemical …)
<br>11.	Mid-term exam 
<br>12.	Biosensors
<br>13.	Molecular Biology on a chip
<br>14.	Cell-ba<x>sed Chips for Biotechnology
<br>15.	BioMEMS for Cell Biology
<br>16.	Implantable Microdevices 
<br>17.	Summary and future perspectives for BioMEMS technology
<br>18.	Final presentation or final exam
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